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IRCT20210415050976N12 IRCT 2023-01-18 Jahrom University of Medical Sciences The effect of intravenous dexmedetomidine on bleeding rate,surgeon satisfaction and hemodynamic stability in patients undergoing septorhinoplasty surgery The effect of intravenous dexmedetomidine on bleeding rate,surgeon satisfaction and hemodynamic stability in patients undergoing septorhinoplasty surgery 2023-01-30 anticipated 74 Complete https://irct.ir/trial/67837 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Randomization description: Sampling will be an easy and accessible sampling of patients undergoing septorhinoplasty surgery during the study period, but the random division of people into two groups (RANDOM ALLOCATION) will be based on a table of random numbers, Blinding description: The researcher and the patient will be unaware of the type of injectable drug and only the anesthesiologist who gives the drug to the specialist will be aware of the type of injected drug. Also, injection syringes were labeled so that the type of drug is not known. 1-2 Cosmetic Surgery. Intervention 1: Intervention group 1: dexmedetomidine (manufactured by Razi Company, 1 mcg/kg per ten minutes along with routine anesthesia and maintenance drugs: 6/. mcg/kg per hour). Intervention 2: Intervention group 2: will receive placebo as the control group.The placebo includes an equal volume of normal saline injection similar to the intervention group. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.
public Navid Kalani
Shahid Motahari Boulevard, Jahrom
Jahrom Iran (Islamic Republic of) 7167758256 +98 71 2536 5231 k.navid@jums.ac.ir Jahrom University of Medical Sciences scientific Navid Kalani
Shahid Motahari Boulevard, Jahrom
Jahrom Iran (Islamic Republic of) 7167758256 +98 71 2536 5231 k.navid@jums.ac.ir Jahrom University of Medical Sciences Iran (Islamic Republic of) Physical status of ASA class I, II Filling out the consent form to participate in the study 15 years 65 years Both Unstable hemodynamics at the moment of entering the operating room (systolic pressure less than 90, diastole less than 60 and heart rate less than 60) Taking drugs affecting hemodynamic status Taking anticoagulants drugs Z41.1 Encounter for cosmetic surgery Treatment - Drugs Treatment - Drugs Intervention group 1: dexmedetomidine (manufactured by Razi Company, 1 mcg/kg per ten minutes along with routine anesthesia and maintenance drugs: 6/. mcg/kg per hour). Intervention group 2: will receive placebo as the control group.The placebo includes an equal volume of normal saline injection similar to the intervention group. Hemodynamic symptoms. Timepoint: Before induction, after induction, 1 minute after induction, 5 minutes after induction, 30, 60, 90 and 120 minutes during operation, entering recovery and exiting recovery. Method of measurement: Monitoring. Consent of the surgeon. Timepoint: During operation every 15 minutes after the start of surgery. Method of measurement: Beozaart scale. Bleeding. Timepoint: During surgery and at the end of the operation. Method of measurement: The amount of blood collected in suction and surgical gases. Jahrom University of Medical Sciences Approved 2022-12-21 Ethics Committee of Jahrom University of Medical Sciences Jahrom University of Medical Sciences, Motahari Street Jahrom Fars Iran (Islamic Republic of)