]>
IRCT20171129037678N1 IRCT 2023-08-09 The University of Mohaghegh Ardabili The effect of saffron and endurance exercise in patients with coronavirus The effect of saffron supplementation and endurance training on the improvement of clinical and laboratory manifestations in outpatients with coronavirus 2023-01-23 anticipated 40 Complete https://irct.ir/trial/67836 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Factorial, Purpose: Supportive, Randomization description: The patient receives the drug (intervention or comparison group) in sealed envelopes that have a code. Coding is done by one of the project colleagues and the doctor, evaluator and patient do not know anything, Blinding description: The patient receives the drug (intervention or comparison group) in sealed envelopes that are coded. Coding is done by one of the colleagues of the project and the doctor, evaluator and patient do not know anything. N/A coronavirus. Intervention 1: Intervention group: patients in this group, in addition to drug treatment according to the national guidelines for the new coronavirus, They receive saffron supplements for 14 days. (400 mg equivalent to 5.7 mg per kilogram of body weight per day). Intervention 2: Control group: Patients in this group receive drug treatment according to the national guidelines for the new coronavirus. Intervention 3: Intervention group: Patients in this group, in addition to the medical treatment according to the national guidelines for the new coronavirus, two weeks of endurance exercise (12 sessions2 hours, four sessions per week, aerobic exercise with an intensity of 65% of the maximum heart rate). Intervention 4: Intervention group: Patients in this group receive saffron supplement for 14 days, in addition to the medical treatment according to the national guidelines for the new coronavirus. (400 mg equal to 5.7 mg per kilogram of body weight per day) plus two weeks of endurance training (12 sessions 2 hours, four sessions per week, aerobic exercise with an intensity of 65% of maximum heart rate). Yes - There is a plan to make this available What will be shared: All data is potentially shareable after de-identifying individuals When: After completing the plan To whom: Only for researchers working in academic and scientific institutions Conditions: For research Where to obtain: Email address of the researcher How to obtain: Email address of the researcher Comments:
public Fateme Halalkhor
Faculty of Physical Education and Sport Sciences, University of Tabriz, 29 Bahman BLVD, Tabriz, East Azarbaijan
Tabriz Iran (Islamic Republic of) 5447135411 +98 41 4224 1099 fateme.halalkhor@gmail.com University of Tabriz scientific Fateme Halalkhor
Faculty of Physical Education and Sport Sciences, University of Tabriz, 29 Bahman BLVD, Tabriz, East Azarbaijan
Tabriz Iran (Islamic Republic of) 5447135411 +98 41 4224 1099 fateme.halalkhor@gmail.com University of Tabriz Iran (Islamic Republic of) Outpatients with covid 19 18 years 65 years Both History of allergy to saffron and its derivatives People with liver, kidney and respiratory disorders Lactating and pregnant women B34.2 Coronavirus infection, unspecified Treatment - Other Placebo Treatment - Other Treatment - Other Intervention group: patients in this group, in addition to drug treatment according to the national guidelines for the new coronavirus, They receive saffron supplements for 14 days. (400 mg equivalent to 5.7 mg per kilogram of body weight per day) Control group: Patients in this group receive drug treatment according to the national guidelines for the new coronavirus. Intervention group: Patients in this group, in addition to the medical treatment according to the national guidelines for the new coronavirus, two weeks of endurance exercise (12 sessions2 hours, four sessions per week, aerobic exercise with an intensity of 65% of the maximum heart rate). Intervention group: Patients in this group receive saffron supplement for 14 days, in addition to the medical treatment according to the national guidelines for the new coronavirus. (400 mg equal to 5.7 mg per kilogram of body weight per day) plus two weeks of endurance training (12 sessions 2 hours, four sessions per week, aerobic exercise with an intensity of 65% of maximum heart rate). Cough. Timepoint: Before and 14 days after the start of treatment. Method of measurement: Physical examination. Breathing rate. Timepoint: Before and 14 days after the start of treatment. Method of measurement: Physical examination. Body temperature. Timepoint: Before and 14 days after the start of treatment. Method of measurement: Physical examination. Speed of improvement. Timepoint: Before and 14 days after the start of treatment. Method of measurement: Physical examination. Inflammatory biomarkers. Timepoint: Before and 14 days after the start of treatment. Method of measurement: blood test. The amount of C-reactive protein. Timepoint: Before and 14 days after the start of treatment. Method of measurement: blood test. Serum level of specific IgG antibody for N and S antigens. Timepoint: One month after training. Method of measurement: Eliza method. The University of Mohaghegh Ardabili Approved 2023-06-20 Ethics Committee of Sport Sciences Research Institute No. 3, Fifth Alley, MirEmad St., Motahari St., Tehran Tehran Tehran Iran (Islamic Republic of)