IRCT20080831001141N41 IRCT 2023-02-08 ROYAN Institute Intra-ovarian injection of platelet-rich plasma in patients with premature ovarian insufficiency Evaluation of intra-ovarian injection of platelet-rich plasma in patients with premature ovarian insufficiency; a clinical trial 2023-02-01 anticipated 54 Complete https://irct.ir/trial/67760 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment, Other design features: A clinical trial without control group, without blinding, phase 3, on 54 patients. N/A Premature ovarian insufficiency. Intervention group: Intervention group: Platelet-rich plasma (PRP) injection will be done on day 8-12 of the menstrual cycle. PRP injection will be performed less than 15 minutes after its preparation by the surgeon and gynecologist. The injection will be done through the vagina, under ultrasound guidance and with a follicle puncture needle. The injection is done under mild anesthesia and takes less than 15 minutes.. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.