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IRCT20100119003106N43 IRCT 2023-02-09 Islamic Azad University Evaluation of the response rate in major depressive disorder after taking citalopram as a predictive factor base on motor cortex magnetic brain stimulation. Evaluation of the response rate in major depressive disorder after taking citalopram as a predictive factor base on motor cortex magnetic brain stimulation. 2023-01-01 anticipated 48 Complete https://irct.ir/trial/67612 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Other, Purpose: Treatment. 2-3 Major Depressive Disorder. Intervention 1: Intervention group :48 patients with major depression in the age group of 18 to 65 years will be selected by a psychiatrist or by using the Hamilton and beck questionnaire and the amount of motor evoked potential will be measured for them before taking the drug. Intervention 2: Control group :Including 48 patients with major depression in the age group of 18 to 65 years approved by a psychiatrist will be selected using the Hamilton and beck questionnaire and the amount of motor evoked potential will be measured for them after taking 20mg citalopram drug. Yes - There is a plan to make this available What will be shared: Age and gender of patients' demographic information as well as the results and questionnaire containing patients' symptoms before and at the end of the treatment period can be shared by removing the individual characteristics of the patients. When: The release time of the documents and files is after the completion of the project and in the spring of 1402. To whom: Researchers working in academic and scientific institutions. Conditions: By observing the ethical principles of information concealment, the documents and all the checks carried out on the information can be published. Where to obtain: Katayun.kiyanipour@gmail.com How to obtain: Sending request E mail Comments:
public Katayoun kiyanipour
No. 99 , Yasaman Alley., Yakhchal street., Gholhak., Dr Shariati street
Tehran Iran (Islamic Republic of) 1941933111 +98 21 4449 7295 Katayun.kiyanipour@gmail.com Islamic Azad University scientific Katayoun keyanipour
No. 99 , Yasaman Alley., Yakhchal street., Gholhak., Dr Shariati street
Tehran Iran (Islamic Republic of) 1941933111 +98 21 4449 7295 Katayun.kiyanipour@gmail.com Islamic Azad University Iran (Islamic Republic of) Diagnosis of major depression by a psychiatrist or by using Hamilton's 24-question questionnaire Age 18-65 years old Having written informed consent and and incentive to cooperate and participate in completing the questionnaires provided by the researcher Not having a history of taking psychiatric drugs in the last 2 weeks 18 years 65 years Both Unwillingness to continue cooperating in the study and not completing the questionnaire If the person is suffering from a specific neurological/psychological disorder at the same time F33 Major depressive disorder, recurrent Treatment - Drugs Treatment - Drugs Intervention group :48 patients with major depression in the age group of 18 to 65 years will be selected by a psychiatrist or by using the Hamilton and beck questionnaire and the amount of motor evoked potential will be measured for them before taking the drug. Control group :Including 48 patients with major depression in the age group of 18 to 65 years approved by a psychiatrist will be selected using the Hamilton and beck questionnaire and the amount of motor evoked potential will be measured for them after taking 20mg citalopram drug. Determining the MEP of patients through TMS. Timepoint: Before taking citalopram and 2 hours after taking citalopram. Method of measurement: Comparison of MEP of patients before and after taking citalopram. Hamilton and Beck depression questionnaire. Timepoint: Before taking citalopram and after taking citalopram. Method of measurement: Comparison of Hamilton and beck depression score of patients before and after taking citalopram. Islamic Azad University Approved 2022-09-26 Ethics committee of Tehran Islamic Azad University of Medical sciences No. 99, Yakhchal street, Gholhak, Dr Shariati street Tehran Tehran Iran (Islamic Republic of)