IRCT20120215009014N457 IRCT 2023-01-10 Hamedan University of Medical Sciences Effect duloxetine versus amitriptyline on clinical outcomes of female with chronic pelvic pain syndrome Effect duloxetine versus amitriptyline on clinical outcomes of female with chronic pelvic pain syndrome: a double-blind randomized clinical trial 2023-01-05 anticipated 48 Complete https://irct.ir/trial/67540 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The patients will be randomly assigned to intervention and control groups using block randomization. For this purpose, we will prepare four sheets of paper, writing on two sheets the name of the intervention and on the other two sheets the name of the control. The paper sheets will be pooled, placed in a container, and randomly drawn one at a time for each patient without replacement until all four sheets are drawn. The four paper sheets will be then placed back into the container, and this action repeated until the sample size is reached, Blinding description: The drugs will be given in coded envelopes. Therefore, patients will be unaware of the type of intervention. The physician who will examine the patients will not be aware of the intervention. Thus, the trial will be run as double-blind. 3 Chronic pelvic pain syndrome. Intervention 1: Intervention group: Duloxetine tablets 30 mg daily for one week then 60 mg daily for 8 weeks. Intervention 2: Control group: Amitriptyline tablets 25 mg daily for one week then 50 mg daily for 8 weeks. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is It depends on the situation and the results of the study as well as the approval of the financial supporting organization.