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IRCT138902141414N14 IRCT 2010-05-28 Endocrinology and Metabolism Research Institute of Tehran University of Medical Sciences Topical T3 Hormone effect in alopecia areata A comparison of Topical T3 Hormone and placebo in treatment of patients with Alopecia Areata 2009-04-01 anticipated 10 Complete https://irct.ir/trial/673 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 2 Alopecia Areata. Intervention 1: Topical T3 cream, 3.8 microgram of T3 in each 30 microgram of novasome A, two times daily for 12 weeks. The patient will apply T3 hormone on one side and placebo on the other side. Intervention 2: Novasome A will be used as placebo and applied in the same way as the intervention group on the other side.
public
scientific Bagher Larijani
Shariati Hospital, North Kargar Ave
Tehran Iran (Islamic Republic of) +98 21 8822 0037 emrc@tums.ac.ir Endocrinology and Metabolism Research Institute of Tehran university of medical sciences Iran (Islamic Republic of) exclusion criteria: 1. clinical or paraclinical evidence of thyroid dysfunction (hypo or hyperthyroidism) 2. paraclinical data confirming abnormality of CBC,LFT 3. patients with Alopecia Totalis or universalis. inclusion: Patients with at least 2 patches of alopecia on 2 different side of body no limit no limit Both L63 Alopecia areata Treatment - Drugs Placebo Topical T3 cream, 3.8 microgram of T3 in each 30 microgram of novasome A, two times daily for 12 weeks. The patient will apply T3 hormone on one side and placebo on the other side. Novasome A will be used as placebo and applied in the same way as the intervention group on the other side Hair regrowth. Timepoint: At the begining, every four weeks and at the end. Method of measurement: Observation and photography. Hair color. Timepoint: at the begining, every4 weeks and at the end. Method of measurement: observation. Endocrinology and Metabolism Research Institute of Tehran University of Medical Sciences Approved 2009-03-01 Endocrinology and Metabolism research institute of Tehran Medical University Shariati Hospital.North Karegar Ave. Tehran Iran (Islamic Republic of)