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IRCT20221126056616N1 IRCT 2022-12-08 Qazvin University of Medical Sciences Investigating and Comparing the Association of Fatty Liver with Tamoxifen and Letrozole in Premenopausal Patients with Breast Cancer Investigating and Comparing the Association of Fatty Liver with Tamoxifen and Letrozole in Premenopausal Patients with Breast Cancer 2022-12-22 anticipated 60 Complete https://irct.ir/trial/67051 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Progesterone receptor or Estrogen receptor positive patients who meet the conditions to enter the study are included in the study by continuous sampling method. They are treated with chemotherapy. They are divided into two groups by random allocation method. The first group of breast cancer patients are treated with Tamoxifen and the second group with Letrozole. 2 Condition 1: Breast Cancer. Condition 2: Fatty Liver. Intervention 1: Intervention group: Patients with Brest cancer treated with Letrozole. Intervention 2: Control group: Patients with Brest cancer treated with Tamoxifen. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Satisfaction of participants
public Mohammad Nazarinia
Bahonar street
Qazvin Iran (Islamic Republic of) 34197-58911 +98 28 3333 6001 m.nazarinia99@gmail.com Qazvin University of Medical Sciences scientific Mohammad Nazarinia
Bahonar street
Qazvin Iran (Islamic Republic of) 34197-58911 +98 28 3333 6001 m.nazarinia99@gmail.com Qazvin University of Medical Sciences Iran (Islamic Republic of) Premenopausal breast cancer patients (Progesterone receptor or Estrogen receptor positive). no limit no limit Female C50 K76.0 Malignant neoplasm of breast Fatty (change of) liver, not elsewhere classified Treatment - Drugs Treatment - Drugs Intervention group: Patients with Brest cancer treated with Letrozole Control group: Patients with Brest cancer treated with Tamoxifen Severity of fatty liver. Timepoint: 6 months after taking tamoxifen and letrozole drugs. Method of measurement: Ultrasound. Qazvin University of Medical Sciences Approved 2022-11-23 Ethics committee of qazvin University of Medical Sciences Research and Technology deputy ,Mavaddat Alley,Shahid Beheshti Blvd,Qazvin Qazvin Qazvin Iran (Islamic Republic of)