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IRCT20100124003146N11 IRCT 2023-03-01 Kashan University of Medical Sciences The effect of astragalus root extract on chronic fatigue syndrome in nurses The effect of astragalus root extract on chronic fatigue syndrome in nurses 2023-03-16 anticipated 64 Complete https://irct.ir/trial/67038 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: The block randomization method will be used in this study. First, the randomization list will be prepared using the online randomization software in blocks of 4. The letter A will be chosen for the intervention group and the letter B will be chosen for the placebo group. Sampling is continuous and then the samples with entry conditions will be placed in groups in order and one after the other based on the previously prepared list of the output of www.sealedenvelop.com online randomization software, Blinding description: The present study is triple blind. The participants will not know the type of group they will be assigned to and will only receive the capsule containing the drug or starch. It should be noted that the drug and placebo are poured into gelatin capsules of the same color. In addition, both substances are white, so the participants cannot notice the type of group when they open the capsules. The second blinding is related to the person prescribing the medicine, who will receive the prepared medicines inside the coded plastic envelopes, and after referring the participant to him, the prescription referee and the code of the envelope will be recorded in the participant's sheet. The third blinded person will be a statistical analyst, whose names of the groups will be entered in the SPSS software and will be available to him. 3 Chronic fatigue syndrome. Intervention 1: Intervention group: Intervention group: In this study, the root extract extracted in hydroalcoholic form is prepared by Barij-Essance company in 500 mg capsules and will be given to the intervention group samples for one month to consume one capsule twice a day (morning and night). Intervention 2: Control group: The samples randomly assigned to the control group received capsules containing corn starch (500 mg per capsule provided by Barij-essence) twice a day for one month, which did not differ in appearance from the root extract. Yes - There is a plan to make this available What will be shared: the results related to the main outcome will be distributed. When: Access will start from the time the results are printed to forever. To whom: Academic and industrial researchers are allowed to submit data requests. Conditions: The applicant must clearly state the purpose of the data request to the person in charge of the data, and if approved by the University Research Council, non-identifiable data will be provided to him. Where to obtain: Dr. Ismail Azizi Fini, email: azizifinies@yahoo.com How to obtain: The data will be sent in less than 24 hours after sending the request via email. Comments:
public Dr Ismail Azizi-Fini
5Th Kilometer Qotb Ravandi blouvar.kashan university of medical sciences
kashan Iran (Islamic Republic of) 8715981151 +98 31 5554 0021 azizifinies@yahoo.com Kashan University of Medical Sciences scientific Dr Esmail Azizi-Fini
5Th Kilometer Qotb Ravandi blouvar.kashan university of medical sciences
Kashan Iran (Islamic Republic of) 8715981151 +98 31 5554 0021 azizi-es@kaums.ac.ir Kashan University of Medical Sciences Iran (Islamic Republic of) Have criteria for chronic fatigue syndrome. 20 to 50 years old. A nurse working in a hospital. Willingness to participate in the study 20 years 50 years Both Unwillingness to continue participating in the study Not taking medicine for 4 consecutive days Lack of access to samples receiving anticoagulants (warfarin-aspirin-coumadin ) Blood pressure drop (systole less than 100 and diastole less than 60) during study continuously or intermittently during the day G93.3 Postviral fatigue syndrome Treatment - Drugs Placebo Intervention group: Intervention group: In this study, the root extract extracted in hydroalcoholic form is prepared by Barij-Essance company in 500 mg capsules and will be given to the intervention group samples for one month to consume one capsule twice a day (morning and night). Control group: The samples randomly assigned to the control group received capsules containing corn starch (500 mg per capsule provided by Barij-essence) twice a day for one month, which did not differ in appearance from the root extract. Chronic fatigue syndrome. Timepoint: At the beginning of the study (before the start of the intervention), the end of the intervention, one month after the end of the intervention. Method of measurement: DePaul Symptom Questionnaire - Short Form (DSQ-SF). Anxiety. Timepoint: At the beginning of the study (before the start of the intervention), the end of the intervention, one month after the end of the intervention. Method of measurement: Beck Anxiety Inventory. Sleep quality. Timepoint: At the beginning of the study (before the start of the intervention), the end of the intervention, one month after the end of the intervention. Method of measurement: Pittsburgh Sleep Quality Index. Kashan University of Medical Sciences Approved 2023-02-13 Faculty of Nursing and Midwifery, Health and Paramedicine - Kashan University of Medical Sciences Qutb Rawandi Blvd kashan Isfehan Iran (Islamic Republic of)