]>
IRCT20221105056407N1 IRCT 2023-03-09 Tabriz University of Medical Sciences Comparison of adding dexmedetomidine to ketorolac and morphine on pain control due to femoral fracture surgery Comparison of adding dexmedetomidine to ketorolac and morphine on pain control due to femoral fracture surgery 2023-03-06 anticipated 200 Complete https://irct.ir/trial/66717 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Factorial, Purpose: Treatment, Randomization description: According to the random number table method, they will be divided into four groups A (dexmedetomidine + morphine), group B (morphine), group C (dexmedetomidine + ketorolac), and group D (ketorolac). The randomization sequence and allocation concealment (placed in sealed envelopes) were performed by a professor in the absence of the working investigators, Blinding description: The volume of injected medicine will be the same for all patients so that the patients will be blinded during the study. Also, the preparation of medicines in the ward will be done by a skilled nurse and only the relevant nurse will know the type of medicine prepared. 3 femoral fracture pain. Intervention 1: Intervention group: Dexmedetomidine + Morphine. Intervention 2: Control group: Morphine. Intervention 3: Intervention group: Dexmedetomidine + ketorolac. Intervention 4: Intervention group: ketorolac. Yes - There is a plan to make this available What will be shared: The data relating to the investigation conducted in the study will be available. When: After publishing of the final report To whom: All individuals can request access to the data and files Conditions: People can reanalyze the data and publish it with the permission of the corresponding author Where to obtain: Marjan Dehdilani, MD Tabriz Shohada hospital 04133893336 md56422@yahoo.com How to obtain: The datasets generated during and/or analyzed during the current study will be available from the corresponding author on reasonable request. Comments:
public Marjan dehdilani
Golestan St, Shohada hospita
tabriz Iran (Islamic Republic of) 629 +98 41 3389 3336 md56422@yahoo.com Tabriz University of Medical Sciences scientific ‌Behrooz Nazari
Golestan St, Shohada hospital
tabriz Iran (Islamic Republic of) 692 +98 41 3389 3336 behrooznazari31@gmail.com Tabriz University of Medical Sciences Iran (Islamic Republic of) patients undergoing femoral fracture length of the surgery should be under 2 hours Spinal anesthesia should be used 18 years no limit Both Patients with BMI of over 30 will be excluded from the study history of addiction to narcotics bleeding more than 1000cc during the surgery multi trauma patients history of anti-anxiety drugs, cardiovascular drugs patients with cardiovascular or renal failure patients with a history of deep vein thrombosis Treatment - Drugs Treatment - Drugs Treatment - Drugs Treatment - Drugs Intervention group: Dexmedetomidine + Morphine Control group: Morphine Intervention group: Dexmedetomidine + ketorolac Intervention group: ketorolac Pain intensity. Timepoint: Pain intensity (measured by Visual Analogue Scale tool) will be measured once every hour for 24 hours. Method of measurement: Visual Analogue Scale. Tabriz University of Medical Sciences Approved 2022-06-01 Ethics Committee of Tabriz University of Medical Sciences Attar neyshabouri St, Tabriz University of Medical Sciences tabriz East Azarbaijan Iran (Islamic Republic of)