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IRCT20221105056400N1 IRCT 2022-12-04 Zanjan University of Medical Sciences Effect of Honey and Trigonella foenum of copd Investigation of the Honey and the Trigonella foenum-graceum L (fenugreek) ‎seeds product effect on chronic obstructive pulmonary Disease: Double – Blinded ‎Trial‏ ‏ 2022-12-29 anticipated 81 Complete https://irct.ir/trial/66672 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: ُSimple randomizationDue to the double-blindness of the study, the doctor, student, and patient will not know about the coding. And the codes are kept with the analyzer and the code given to each patient will be recorded on the patient information registration for, Blinding description: Direction of Double blind study، doctor medical، student and patient dont know of cods. 3 Cronic Obstructive Pulmonary Deasese. Intervention group:: Patients will be divided into three groups of 27 people and one group will receive placebo and the second group will receive honey syrup and the third group will receive a combination of honey and fenugreek products for 4 weeks. Fenugreek syrup products and Honey and honey syrup will be prepared at the Faculty of Pharmacy of Zanjan University of Medical Sciences and after checking and verifying the quality of herbal ingredients and honey and chemical and microbial stability, the products will be prescribed to patients.The product of fenugreek and honey will be standardized by checking the amount of total saponin based on the active substance Diosgenin. Patients are given a daily amount of syrup containing the extract obtained from 5 grams of fenugreek powder in 2 A divided dose will be prescribed. According to previous studies, the amount of honey will be 40 grams of honey per 100 ml in honey and fenugreek syrup, and honey and placebo syrup will be based on 40 grams of sweetener per 100 ml.. Yes - There is a plan to make this available What will be shared: All data cannot be shared after de-identifying individuals, but part of the information related to the main outcome can be shared When: Start accessing results 6 months later To whom: Researchers working in academic and scientific institutions and people in the pharmaceutical industry Conditions: in order to study students and researchers, especially in the field of herbal medicines and traditional pharmaceuticals, under research-oriented conditions and to continue studies in the field of traditional medicine and other valid fields in the field of health and medicine. Where to obtain: My email, mobile number How to obtain: Six months later, the article was published Comments:
public Dr Parisa Jafari
Above Valiasr Square, Valiasr Medical Training Center, Traditional Medicine Clinic
زنجان Iran (Islamic Republic of) 45157-77978 +98 24 3377 0801 Parisa.jafari.1349@gmail.com Zanjan University of Medical Sciences scientific Dِr Parisa JAFARI
Above Valiasr North Square, Valiasr Hospital
Zanjan Iran (Islamic Republic of) 45157-77978 +98 24 3377 0801 Parisa.jafari.1349@gmail.com Zanjan University of Medical Sciences Iran (Islamic Republic of) Moderate COPD Deasese diagnosed with Pulmonologist Deasese with stable condition Deasese age 30-60 deasese with self consent 30 years 60 years Both Deasese with Diabet Melitos Deasese with Alergy Honey and Trigonella foenum Deasese with Pregnancy or Lactation Deasese with sever COPD Deasese with Underlying deasese such as CF.Heart Failre.Pulmonal Amboly.Ressistant HTN Deasese with Pulmonal canser or other cansers j44.1 j44.1 Treatment - Drugs Intervention group:: Patients will be divided into three groups of 27 people and one group will receive placebo and the second group will receive honey syrup and the third group will receive a combination of honey and fenugreek products for 4 weeks. Fenugreek syrup products and Honey and honey syrup will be prepared at the Faculty of Pharmacy of Zanjan University of Medical Sciences and after checking and verifying the quality of herbal ingredients and honey and chemical and microbial stability, the products will be prescribed to patients.The product of fenugreek and honey will be standardized by checking the amount of total saponin based on the active substance Diosgenin. Patients are given a daily amount of syrup containing the extract obtained from 5 grams of fenugreek powder in 2 A divided dose will be prescribed. According to previous studies, the amount of honey will be 40 grams of honey per 100 ml in honey and fenugreek syrup, and honey and placebo syrup will be based on 40 grams of sweetener per 100 ml. Disease score based on reliability of chronic obstructive pulmonary disease(cat). Timepoint: Clinical examination and reliability of the disease at the beginning of the study (before intervention) 7, 14 and 21 and after consuming fenugreek and honey syrup at the end of the stud. Method of measurement: Reliability questionnaire of chronic obstructive pulmonary disease( cat ) and spirometry. The secondary outcome is the improvement of activity dyspnea and energy level and sleep. Timepoint: Before starting the study, on the 7th, 14th, 21st, and then, take fenugreek and honey syrup. Method of measurement: Reliability standard guidelines for chronic obstructive pulmonary diseases (cat). The secondary outcome is the improvement of activity dyspnea and energy level and sleep. Timepoint: Before starting the study, on the 7th, 14th, 21st, and then, take fenugreek and honey syrup. Method of measurement: Reliability standard guidelines for chronic obstructive pulmonary diseases (cat). Research and Technology of Zanjan University of Medical Sciences (Dr. Samad Nedri) Approved 2022-11-02 IR.ZUMS.REC.1401.220 Blvd. of Ostad Saboti, Zanjan University of Medical Sciences Zanjan Zanjan Iran (Islamic Republic of)