IRCT20221010056141N1 IRCT 2022-12-20 Shahid Beheshti University of Medical Sciences Effect of Betamethasone in mothers with PROM Evaluation of the effect of a complete course of betamethasone on neonatal and mothers with Premature rupture of membranes at 34 to 36 weeks of pregnancy 2023-01-21 anticipated 200 Complete https://irct.ir/trial/66323 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization in such a way that the last digit of the patient file number is placed in the intervention group if it is even, and in the control group if it is odd, Blinding description: data collection and information analysis group will be unaware of the placement of the patient in the test or control group.The primary data will be provided to the data analysis group without mentioning the name of the group in the form of group A, B. 3 Premature Rupture of Membrane. Intervention 1: Mothers with premature rupture of membrane between 34 to 36 weeks of gestational age, in which betamethasone ampoule with a dose of 12 mg (3 ampoules of 4 mg at once) is injected intramuscularly into the Gluteus muscle. 24 hours later, the second dose will be repeated in the same way. Betamethasone ampoule used is a product of Caspian Pharmaceutical Company. Intervention 2: Control group: Pregnant women with premature rupture of membrane that Betamethasone was not injected at 34 to 36 week of gestational age. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information