IRCT20220919055992N1 IRCT 2022-11-03 Iran University of Medical Sciences Comparison of the use of the cardioplegic material through the descending and ascending aorta in organ donation Comparison of the use of the cardioplegic material through the descending and ascending aorta in the simultaneous removal of the heart and liver in organ donation: a randomized controlled clinical trial phase II 2022-10-21 anticipated 54 Complete https://irct.ir/trial/66279 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Each of the patients will be randomized by sealed envelope before the intervention, Blinding description: This study is a double-blind clinical trial and only the operating surgeon of the study has the complete information of each patient. The rest of the medical team performing before and after surgery observations are not aware of patients’ study group. 2 Donors of organs and tissues. Intervention 1: Intervention group: This group contains organ donors who undergo an injection of a cardioplegic solution to descending aorta. Firstly sternotomy, complete isolation of aortic arch arteries, and simultaneous ligation of azygus and superior vena cava will be done then abdominal aorta cannulation after preparation of abdomen, clamp of ascending aorta and opening of inferior pulmonary vein and inferior vena cava will be performed. Finally we remove the heart and liver. Intervention 2: control group: Organ donors who undergo injection of a cardioplegic solution to ascending aorta. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information