<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20221004056085N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2022-10-07</date_registration>
      <primary_sponsor>Government College University Faisalabad</primary_sponsor>
      <public_title>Effects of Aerobic training for Improving  Functional Mobility in Coronary Artery Bypass Graft Patients</public_title>
      <acronym>CABG</acronym>
      <scientific_title>Effects of Preoperative Aerobic training for Improving Postoperative Functional Mobility in Coronary Artery Bypass Graft Patients</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2022-05-20</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>38</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/66171</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Coronary artery bypass graft is a surgical operation in which blocked arteries are partially or completely bypass using grafts taken from other arteries or veins. a therapeutic procedure used to treat coronary artery disease..</hc_freetext>
      <i_freetext>Intervention 1: Aerobic training group. Warm up activity include range of motion exercises of upper and lower limb (8-12 repetitions) one set in a day. Aerobic exercises in the form of walking on flat surface in corridor, light to moderate pace(10-15 min).Stepping (8-12 repetitions) once a day , 4 days in a week for 3 weeks.Cool down activity include static stretching(20-60 sec hold) exercise of upper and lower limb one set in a day. As in conventional group treatment. Intervention 2: Conventional group. Early mobilization( bed mobility, transfer) according to the protocol. Deep breathing exercises include Diaphragmatic and Pulse lip breathing.In this exercise breath in deeply and slowly through your nose, expanding your lower rib cage and letting your abdomen move forward,hold for a count 3-5. Breath out slowly and completely through your pulsed lips, once a day, 4 days in a week for 3 weeks. Huff and cough technique once a day, 4 days in a week for 3 weeks.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Undecided - It is not yet known if there will be a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for indecision in sharing IPD is There is no further information</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Usama Munir</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Street no 5, Awami Colony, Milad Road, Faisalabad</address>
        <city>Faisalabad</city>
        <country1>Pakistan</country1>
        <zip>38000</zip>
        <telephone>+92 332 6621129</telephone>
        <email>usamamunir7209@gmail.com</email>
        <affiliation>Government College University Faisalabad</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Usama Munir</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>street no 5, Awami colony, Milad road, Faisalabad</address>
        <city>Faisalabad</city>
        <country1>Pakistan</country1>
        <zip>38000</zip>
        <telephone>+92 332 6621129</telephone>
        <email>usamamunir7209@gmail.com</email>
        <affiliation>Government College University Faisalabad</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Pakistan</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Age 40-60 years
Patients awaiting coronary artery bypass graft patients with stable angina
Patients with double and triple coronary artery disease
Patients with left ventricular ejection fraction &gt;50%
Patients who have diabetes
Patients who are smokers
Patients who have hypertension</inclusion_criteria>
      <agemin>40 years</agemin>
      <agemax>60 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria>Patients with congestive heart failure
Patients having dysrhythmias and pacemaker dependent
Patients with neurological deficit( stroke, epilepsy, Alzheimer disease)
Patients with renal dysfunction require dialysis
Concomitant valve disease
Patients with pulmonary complications</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>T82.2</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Mechanical complication of coronary artery bypass graft and biological heart valve graft</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Rehabilitation</i_code>
      <i_code>Rehabilitation</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Aerobic training group. Warm up activity include range of motion exercises of upper and lower limb (8-12 repetitions) one set in a day. Aerobic exercises in the form of walking on flat surface in corridor, light to moderate pace(10-15 min).Stepping (8-12 repetitions) once a day , 4 days in a week for 3 weeks.Cool down activity include static stretching(20-60 sec hold) exercise of upper and lower limb one set in a day. As in conventional group treatment.</i_keyword>
      <i_keyword>Conventional group. Early mobilization( bed mobility, transfer) according to the protocol. Deep breathing exercises include Diaphragmatic and Pulse lip breathing.In this exercise breath in deeply and slowly through your nose, expanding your lower rib cage and letting your abdomen move forward,hold for a count 3-5. Breath out slowly and completely through your pulsed lips, once a day, 4 days in a week for 3 weeks. Huff and cough technique once a day, 4 days in a week for 3 weeks.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Time up and go test  was used to measure the functional mobility of the patients. record the readings in seconds in time up and go test. Timepoint: 3 time-points including Baseline, 3rd week preoperative, postoperative before discharge. Method of measurement: Time up and go test will be utilized to access functional mobility.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>Canadian cardiovascular society grading  is a grading scale used to grade the angina of patients. There are 4 grade of it. Grade 1 mean ordinary physical activity does not cause angina. Grade 2 mean slight limitation of ordinary physical activity. Grade 3 mean marked limitation of ordinary physical activity. Grade 4 mean inability to carry on any physical activity. Timepoint: 3 time-points including Baseline, 3rd week preoperative, postoperative before discharge. Method of measurement: CCS will be used to grading the angina of patients.</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Self financed</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2022-04-17</approval_date>
        <contact_name>Name of ethics committee: Ethical committee of Government College University Faisalabad</contact_name>
        <contact_address>Kotwali Rd, Gurunankpura, Faisalabad, Punjab 38000 Faisalabad Punjab Pakistan</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
