<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20220414054537N4</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2022-10-16</date_registration>
      <primary_sponsor>Committe Azra Naheed Centre for Research &amp; Development the Superior University</primary_sponsor>
      <public_title>Effect of mulligan (Natural Apophyseal Glides &amp; Natural Sustained Apophyseal Glides) and Mckenzie (self Stretching) on improving the pain and functional ability in patients with chronic neck pain</public_title>
      <acronym></acronym>
      <scientific_title>Compare the effectiveness of Mulligan (Natural Apophyseal Glides &amp; Natural Sustained Apophyseal Glides) and McKenzie (self-stretching) on improving the pain and functional ability in patients with Chronic Neck pain.</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2022-09-01</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>26</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/66155</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Participants who fulfilled the inclusion criteria were selected convenient sampling technique and were then allocated randomly to Group A and Group B using the lottery method. In this method the selected total population, the divided into two groups. each member of the population has an equal chance to be get selected for any group A or B. that was selected for  This distribution process is hidden between participants and researchers. This was done by a research assistant who did not participate in any further research, Blinding description: This study was double-blinded. The outcome assessor who was blinded to the therapy group was
recruited to take readings at pre-treatment and post-treatment values. And the patients were also
blinded as they didn’t know they all have the same disorder and different techniques had been
given to these patients.</study_design>
      <phase>1</phase>
      <hc_freetext>Chronic neck pain.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group:  We applied the mulligan technique of manual therapy treatment that included the Natural apophyseal glides, Sustained natural apophyseal glides in the sitting position of the patient. Natural apophyseal glide movements are the oscillatory Movement and these mobilizations tend to be provided in the anterior-cranially direction of the selected cervical joint. The movement of the force is in a parallel direction toward the restricted cervical facet joints. We applied 3 sets of 6 repetitions each and the intensity of dosage was maintained in 2-3 hertz. The procedure of the movement as per the following instruction of the mulligan in which we applied the sustained glide and asked the patient to move their neck in several directions like Flexion, Extension, Side flexion, and rotation and this movement was maintained in pain-free direction and range. Intervention 2: Intervention group: The second group of 13 patients with chronic neck pain was given the following treatment strategies which we applied the Mackenzie exercises in seven motions 4 movements of neck extension,2 movements in lateral flexion and rotation, and one movement in flexion direction. The pre and post value was monitored by performing the Mackenzie technique in the patient and its effect on the body was also monitored as well, especially in the soft tissue area of the neck body. Both sides of the body were measured and compared with each other. The time to take the new reading is 10 seconds. the Body skin of the neck area was pushed by 0.18 N force and after the pre-load, a force of 0.58N was applied to the neck skin at the intervel of 15 ms. Thereafter, the vibration on the skin surface was triggered by Myoton PRO (Myoton AS, Estonia), a muscle tone measurer, which was used to examine the biomechanic indices.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Yes - There is a plan to make this available</results_IPD_plan>
      <results_IPD_description>What will be shared:
Compare the effectiveness of Mulligan Natural Apophyseal Glides &amp; Sustained Natural apophyseal Glides and McKenzie (self-stretching) on improving pain and functional ability in patients with Chronic Neck pain.
The data document related to the research will be available after the completetion of the trail. These document will be available like , Patient performa, Data anlysis , spss file , result for the further studies and better patient care

When:
When the trial has been completed after the end october 2022.The data will be available for the future use and after the completion of the trial when it get published approximately after the 3 weeks in the end of the november 2022.The summary will be available after the article get published

To whom:
It will be available to all teaching institue and hospital for the better cure of the patient and more over it will be avilable for the researcher as well

Conditions:
Only for the research and for the benefits of the public

Where to obtain:
The Documents will be available on the following details email.: rehanfaisal68@gmail.com Contact no: +923334816348 Postal address: Department of Physical Therapy Chaudary Akram Teaching Hospital,The Superior Univeristy Lahore

How to obtain:
Application will sent to the email on request rehanfaisal68@gmail.com

Comments:
</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Dr Zohaib Shahid</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Main Riwind Road 17 km ,Lahore</address>
        <city>Lahore</city>
        <country1>Pakistan</country1>
        <zip>54000</zip>
        <telephone>+92 333 4816348</telephone>
        <email>zohaib.rana@Superior.edu.pk</email>
        <affiliation>Committe Azra Naheed Centre for Research &amp; Development the Superior University ,Lahore</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Dr Zohaib Shahid</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>main riwind road 17 km ,Lahore</address>
        <city>Lahore</city>
        <country1>Pakistan</country1>
        <zip>54000</zip>
        <telephone>+92 333 6979114</telephone>
        <email>zohaib.rana@Superior.edu.pk</email>
        <affiliation>Committe Azra Naheed Centre for Research &amp; Development the Superior University ,Lahore</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Pakistan</country2>
    </countries>
    <criteria>
      <inclusion_criteria>. The ages of the patients were around 20-55 years old
The entire patient having the mechanical neck pain and pain due abnormal posture of neck like forward head posture were included in this study
All the patients that were Included for the study should based on Biondi questionnaire
All the patients should have greater than 20% neck disability index score and the score of Numeric pain rating will be more than 2-3 points</inclusion_criteria>
      <agemin>20 years</agemin>
      <agemax>55 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria>All participants were excluded from this study if they had any hearing problem, vision disorder, smell issues or any kind of taste related problem
All participant those were having any systematic problems, like tension headache, Rheumatic arthritis, several viral and bacterial infection, Inflammatory disease, migraine,
any neurological problem and fracture in neck region were excluded from this study</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>M54. 2</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Neck Pain</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Rehabilitation</i_code>
      <i_code>Rehabilitation</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group:  We applied the mulligan technique of manual therapy treatment that included the Natural apophyseal glides, Sustained natural apophyseal glides in the sitting position of the patient. Natural apophyseal glide movements are the oscillatory Movement and these mobilizations tend to be provided in the anterior-cranially direction of the selected cervical joint. The movement of the force is in a parallel direction toward the restricted cervical facet joints. We applied 3 sets of 6 repetitions each and the intensity of dosage was maintained in 2-3 hertz. The procedure of the movement as per the following instruction of the mulligan in which we applied the sustained glide and asked the patient to move their neck in several directions like Flexion, Extension, Side flexion, and rotation and this movement was maintained in pain-free direction and range</i_keyword>
      <i_keyword>Intervention group: The second group of 13 patients with chronic neck pain was given the following treatment strategies which we applied the Mackenzie exercises in seven motions 4 movements of neck extension,2 movements in lateral flexion and rotation, and one movement in flexion direction. The pre and post value was monitored by performing the Mackenzie technique in the patient and its effect on the body was also monitored as well, especially in the soft tissue area of the neck body. Both sides of the body were measured and compared with each other. The time to take the new reading is 10 seconds. the Body skin of the neck area was pushed by 0.18 N force and after the pre-load, a force of 0.58N was applied to the neck skin at the intervel of 15 ms. Thereafter, the vibration on the skin surface was triggered by Myoton PRO (Myoton AS, Estonia), a muscle tone measurer, which was used to examine the biomechanic indices</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Neck Pain. Timepoint: Before Interention and after 8 weeks. Method of measurement: Numeric Pain Rating Scale.</prim_outcome>
      <prim_outcome>Functional Ability. Timepoint: Before and after 8 weeks. Method of measurement: Neck Disability Scale.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Chaudhary Akram Teaching Hospital</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2022-08-28</approval_date>
        <contact_name>Committe Azra Naheed Centre for Research &amp; Development the Superior University ,Lahore</contact_name>
        <contact_address>Main riwind road 17 km ,Lahore Lahore Punjab Pakistan</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
