IRCT20220208053971N2 IRCT 2022-12-09 Tehran University of Medical Sciences The effect of oral nutrition supplement (ONS) on autologous hematopoietic stem cell transplantation The effect of oral nutrition supplement (ONS) on nutritional and clinical status of patients undergoing autologous hematopoietic stem cell transplantation 2022-12-17 anticipated 38 Complete https://irct.ir/trial/66075 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Stratified block randomization will be performed based on the sex and age and using the site www.randomization.com. In this method, each group will be assigned one of the letters A and B, and randomization will be done in blocks with size of 4 . This will be done for sex (male and female) and age (18-35 and 35-50 years old). Within each class, patients will be randomly assigned to one of the two study groups in a 1: 1 ratio. The randomization process will be performed by someone outside the research team. 2 Condition 1: Lymphoma. Condition 2: multiple myeloma. Intervention 1: Intervention group: The type of intervention in the treatment group will be an oral nutritional supplement of 500 kcal, including carbohydrates, fat, protein, vitamins, and minerals. The formula will be given to patients in the amount of 250 ccs in the morning and bedtime snacks. The control group will not receive any supplements. The intervention will be carried out for 21 days and we will follow up with the patients until 90 days after the transplant. Intervention 2: Control group: The control group will not receive any supplements. No - There is not a plan to make this available Justification or reason for not sharing IPD is Due to the confidentiality of participant information, it is not possible to publish it.