IRCT20120718010324N75 IRCT 2022-12-10 Tabriz University of Medical Sciences The effect of magnesium on depression and sleep quality and quality of life in postmenopausal women The effect of magnesium on depression and sleep quality and quality of life in postmenopausal women: a randomized controlled trial 2022-12-21 anticipated 82 Complete https://irct.ir/trial/65703 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Participants in the study will be assigned to two groups of intervention (recipient of magnesium pill) and control (recipient of placebo pill) by block randomization method with block sizes of 4 and 6 and a allocation ratio of 1: 1 and using the website www.random.org . To hide the Allocation (Allocation Concealment), the allocation sequence will be identified by a person not involved in the study using a randomizer, and the magnesium and placebo will be placed in the same packages numbered sequentially, Blinding description: The participants, researcher and data analyst will be blinded completely in this study. Drug and placebo will be similar in appearance (shape, color, smell) and packaging of drug and placebo will be conducted by a person not involved in the research. 3 Condition 1: Depression. Condition 2: Sleep quality. Intervention 1: Intervention group: Each person will receive 90 magnesium tablets of 250 mg made by Galenus company for 12 weeks. One tablet will be taken daily with a glass of water. Intervention 2: Control group: Each person will receive 90 placebo tablets similar to magnesium tablets made by Galenus for a period of 12 weeks. One tablet will be taken daily with a glass of water. No - There is not a plan to make this available Justification or reason for not sharing IPD is Participant data is confidential.