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IRCT20130723014122N2 IRCT 2023-04-24 Effect of celecoxib on symptoms of patients with Schizophrenia under Electroconvulsive Therapy Effect of celecoxib on symptoms of patients with Schizophrenia under Electroconvulsive Therapy 2023-04-21 anticipated 48 Complete https://irct.ir/trial/65655 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: For this purpose, we used the quadruple random block method. For this purpose, we prepare four sheets of paper for each drug and placebo group separately. We write the letter A (intervention group) on two sheets and the letter C (comparison group) on the other two sheets.We mix the sheets together and put them in the desk drawer. With the referral of each of the eligible patients, one of the sheets was randomly drawn and based on this drawn sheet, A or C was assigned to one of the two intervention groups (celecoxib) and the control group (placebo), respectively.It should be noted that the drawn cards are not returned to the drawer until all four cards are drawn. After randomly pulling out fourteen sheets, all the sheets were returned to the drawer and the above operation was continued for the next four patients until the desired sample size was reached, Blinding description: We use the block method for blinding. According to the study, there are 2 modes. State A (Celecoxib drug) State B (Placebo) The order of random placement of these two modes is 6 types. We write these 6 species and assign a number to each one. For example -/1- -/AABB To write the table, we randomly pick a number from among the written numbers and write the state of that number in the table. When the table is filled with the number of participants, we proceed according to the table. For the first participant, we choose the first block, which is, for example, A, and for the second participant, we choose the second block, which is, for example, A again, and move on. N/A Schizophrenia. Intervention group: celecoxib + ECT and routine drugs, control group: placebo + ECT and routine drugs. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information
public Azad Maroufi
Pasdaran street below the Pardis, Ghods hospital, Sanandaj
Sanandaj Iran (Islamic Republic of) 66177_13446 +98 87 1666 4646 marufi@muk.ac.ir Sanandaj University of Medical Sciences scientific Azad Maroufi
Pasdaran street below the Pardis, Ghods hospital, Sanandaj
Sanandaj Iran (Islamic Republic of) 66177_13446 +98 87 1666 4646 marufi@muk.ac.ir Sanandaj University of Medical Sciences Iran (Islamic Republic of) patients with Schizophrenia under Electroconvulsive Therapy 18 years 60 years Both Treatment - Drugs Intervention group: celecoxib + ECT and routine drugs, control group: placebo + ECT and routine drugs Blood biochemical indicators: CBC diffWBCBaselin monocyte LymphocyteESRCRP. Timepoint: Before the start of shock therapy, the end of the third session and the end of the sessions. Method of measurement: Review of clinical findings. Sanandaj University of Medical Sciences Sanandaj University of Medical Sciences Approved 2022-09-13 Ethics committee of Kurdistan University of Medical Sciences Pasdaran Ave, Shohadaye Nirooye Entezami Blve., Qods Hspital Sanandaj Kurdistan Iran (Islamic Republic of)