<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20161026030516N2</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2022-09-21</date_registration>
      <primary_sponsor>Tehran University of Medical Sciences</primary_sponsor>
      <public_title>Comparison of transcranial stimulation and stretching exercises on mental fatigue  in slump posture</public_title>
      <acronym></acronym>
      <scientific_title>Comparison of the effects of transcranial direct current stimulation and stretching exercises on mental fatigue using electroencephalographic parameters in people with slump posture</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2022-10-12</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>60</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/65653</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Crossover, Purpose: Diagnostic.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Slump posture.</hc_freetext>
      <i_freetext>Intervention 1: First intervention group: in the present study, stretching exercises for trunk, neck and upper limb muscles are selected and taught to people. In total, it takes 10 minutes to do the exercises, This intervention is for the slump posture group to do before typing in one session.The interval between each session is considered to be one week, and the order of people's attendance in these sessions is  follows: It  randomly. Intervention 2: Intervention group 2:  Another intervention is the use of transcranial direct  stimulation. In the current study, the NEUROSTIM2 device produced by Medina Medicine Company of Iran will be used to provide electrical stimulation. The intervention is carried out using 3 x 5 cm square carbon plate electrodes with wet sponge coating. According to previous studies, stimulation of the left posterior lateral prefrontal cortex improves cognitive functions such as decision making, attention and working memory. Therefore, to stimulate this area, the anode electrode is placed on the F3 point according to the international 10-20 system, and the cathode electrode is placed on the opposite supraorbital area. To reduce skin resistance, the desired area is cleaned with cotton and alcohol as much as possible. The intensity of the stimulation will be 2 mA and its duration will be 10 minutes. The current first increased  during the first 30 seconds to reach  2 mA and this value is maintained during 10 minutes until the last 30 s,that it  reduces to 0. During the application of the current and also after its completion, the physical and mental conditions of the patient will be checked and if any side effects or discomfort are reported, the application of the current will be stopped if necessary. People in the posture slump group receive it in one of the three sessions of participating in the study, before typing.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Undecided - It is not yet known if there will be a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for indecision in sharing IPD is there is no more information</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Zahra Abdollahzade</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Darvazeh Shemiran, Enqelab St.,Tehran</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>11489-65111</zip>
        <telephone>+98 21 7753 3939</telephone>
        <email>z-abdollahzade@razi.tums.ac.ir</email>
        <affiliation>Tehran University of Medical Sciences</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Zahra Abdollahzade</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Darvazeh Shemiran, Enqelab St.,Tehran</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>11489-65111</zip>
        <telephone>+98 21 7753 3939</telephone>
        <email>z-abdollahzade@razi.tums.ac.ir</email>
        <affiliation>Tehran University of Medical Sciences</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Age between 20 and 40 years old
Not having visual impairments
Craniovertebral angle more than 50 degrees and kyphosis between 20 and 40 degrees for the correct posture group and craniovertebral angle less than 50 degrees and kyphosis more than 40 degrees for the slump posture group
Having at least a diploma
Fluency in Persian language
Computer typing experience and lack of ten-finger typing skills
No history of chronic or acute diseases such as neurological, cardiac or metabolic diseases
No history of mental illnesses
scoring 24 or higher on the Short Mental Status Examination (MMSE)
musculoskeletal discomfort less than 7.5 based on the visual analog scale, due to the prevention of its impact on cognitive function
no history of shoulder and spine surgery
No history of fractures or spinal diseases
Absence of obvious scoliosis
BMI less than 30 kg/m2
Not taking any drugs affecting motor and cognitive function
Not consuming stimulant drinks such as coffee and alcohol 48 hours before participating in the study</inclusion_criteria>
      <agemin>20 years</agemin>
      <agemax>40 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria>Unwillingness to continue the test or confusion and inability to continue the test.
Pregnancy</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>R29.3</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Abnormal posture</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Treatment - Other</i_code>
      <i_code>Treatment - Other</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>First intervention group: in the present study, stretching exercises for trunk, neck and upper limb muscles are selected and taught to people. In total, it takes 10 minutes to do the exercises, This intervention is for the slump posture group to do before typing in one session.The interval between each session is considered to be one week, and the order of people's attendance in these sessions is  follows: It  randomly.</i_keyword>
      <i_keyword>Intervention group 2:  Another intervention is the use of transcranial direct  stimulation. In the current study, the NEUROSTIM2 device produced by Medina Medicine Company of Iran will be used to provide electrical stimulation. The intervention is carried out using 3 x 5 cm square carbon plate electrodes with wet sponge coating. According to previous studies, stimulation of the left posterior lateral prefrontal cortex improves cognitive functions such as decision making, attention and working memory. Therefore, to stimulate this area, the anode electrode is placed on the F3 point according to the international 10-20 system, and the cathode electrode is placed on the opposite supraorbital area. To reduce skin resistance, the desired area is cleaned with cotton and alcohol as much as possible. The intensity of the stimulation will be 2 mA and its duration will be 10 minutes. The current first increased  during the first 30 seconds to reach  2 mA and this value is maintained during 10 minutes until the last 30 s,that it  reduces to 0. During the application of the current and also after its completion, the physical and mental conditions of the patient will be checked and if any side effects or discomfort are reported, the application of the current will be stopped if necessary. People in the posture slump group receive it in one of the three sessions of participating in the study, before typing.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Mental fatigue. Timepoint: Before and after of typing. Method of measurement: visual analog scale-fatigue.</prim_outcome>
      <prim_outcome>Musculoskeletal discomfort. Timepoint: Before and after typing. Method of measurement: visual analog scale.</prim_outcome>
      <prim_outcome>Number of typing errors. Timepoint: After typing. Method of measurement: Counting by the examiner.</prim_outcome>
      <prim_outcome>Typing speed. Timepoint: After typing. Method of measurement: It is calculated by the examiner as the number of words per minute.</prim_outcome>
      <prim_outcome>Entropy of the head, neck, trunk and pelvis. Timepoint: The first and last three minutes of typing. Method of measurement: Marker and filming.</prim_outcome>
      <prim_outcome>The relative power of the frequency spectrum. Timepoint: The first and last three minutes of typing. Method of measurement: Electroencephalography device.</prim_outcome>
      <prim_outcome>ERD/ERS. Timepoint: The first and last three minutes of typing. Method of measurement: Loretta software.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Tehran University of Medical Sciences</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2022-08-20</approval_date>
        <contact_name>Ethics Committee of Tehran university of medical science</contact_name>
        <contact_address>Central office of TUMS, Ghods St., Keshavarz blvd., Tehran Tehran Tehran Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
