IRCT20220809055651N1 IRCT 2022-10-30 Kashan University of Medical Sciences PRP in infertility PRP in infertility Evaluation of the effect of PRP on the outcome of IVF cycle in poorly responding patients 2022-10-23 anticipated 15 Complete https://irct.ir/trial/65263 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment, Other design features: Hematological disorders (leukemia, thrombocytopenia), immunological disorders (antiphospholipid syndrome, thrombophilia), hormonal disorders (diabetes, thyroid, hyperprolactinemia), chromosomal and genetic abnormalities (hereditary or congenital) and kidney failure. 2 Evaluation of the effect of PRP on the outcome of IVF cycle in poorly responding patients. The present study is a before and after clinical trial study that will be conducted in Shahid Beheshti Hospital, Kashan. This study will be conducted on 15 poor responder patients of group 3 and 1 poseidon. The IVF cycle begins with the administration of HMG at a dose of 300 IU/d, and on the fifth day, ultrasound stimulation is performed again. If a follicle with a size of 12 to 14 micrometers is observed, the patient is prescribed Sterotide (MG0.25). When 2 or more than 2 follicles with a size of 17 or more than 17 mm are seen in ultrasound,The final follicle stimulation is done by prescribing HCG 10000 + ptyl 0.2mg Decape for the patient. HMG Vestrotide brand is one of the drugs available in the market and PRP is Avigen brand. 36 hours after the final follicle stimulation, the ovary is punctured and after the puncture at the rate of 2.5 CC PRP is injected into each ovary. 3 months after PRP administration, FSH and AMH levels are measured in the same people, and IVF cycles are performed again with the same method as before, and the number of follicles with a size of 17 micrometers or more, the number of M2 oocytes, the percentage of fertilization, the number of embryos and the quality The embryo and the thickness of the endometrium are examined. Finally, all these criteria that were mentioned are compared with the time before PRP administration.. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information