IRCT201407206063N3 IRCT 2014-08-11 Tehran University of Medical Science and Health Service FSH effect in OHSS prevention FSH,hCG,OHSS Administration of bolus follicle stimulating hormone (FSH) with trigger dose human chorionic gonadotropin (hCG) in prevention of ovarian hyperstimulation syndrom (OHSS) 2014-07-30 anticipated 70 Complete https://irct.ir/trial/6519 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. 2-3 OHSS. Intervention 1: cases give one dose of 450 IU of FSH sub cutaneous at the time of the hCG trigger. Patients will followed at days 3, 10 post oocyte retrieval. Symptoms of OHSS (lower abdominal discomfort, abdominal distension, nausea and/or vomiting, rapid weight gain, dyspnea,and progressive oliguria), volumes of ovaries and ascites will observe . Intervention 2: For control group hCG trigger administer as usual method , then they will followe at days 3, 10 post oocyte retrieval. Symptoms of OHSS (lower abdominal discomfort, abdominal distension, nausea and/or vomiting, rapid weight gain, dyspnea,and progressive oliguria), volumes of ovaries and ascites will observe .