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IRCT20220802055602N1 IRCT 2022-08-20 Kerman University of Medical Sciences The effect of curcumin supplementation on pain caused by neuropathy in patients treated with taxanes کورکومین و نوروپاتی داروی شیمی درمانی The effect of curcumin supplementation on pain caused by neuropathy in patients treated with taxanes 2022-08-11 anticipated 60 Complete https://irct.ir/trial/65099 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Single, Purpose: Supportive, Randomization description: Simple, individual randomization is random allocation to intervention and control groups through a table of random numbers, Blinding description: Drugs will be coded by a third party (external to the study) (eg, main treatment group #1, placebo #2, and positive control #3). Then the drug label will be removed and the numbered drugs will be given to the student (responsible for following up and correct prescription of drugs). The student only sees the number and does not know the type of medicine. The patient only knows that he is participating in a study that will help his treatment process and is completely unaware of the prescription of the type of medicine to be taken. After prescribing the drugs and recording the data by the student, the information is provided to the statistical analyst (who also only knows the number and does not know the type of drug). After the statistical analysis, the data will be provided to the researcher responsible for writing the article. In order to write the article, the main researcher will match the number of drugs with their type by referring to a third party (outside the study). 3 Condition 1: Neuropathy caused by receiving taxanes. Condition 2: cancer. Intervention group: patients with chemotherapy-induced neuropathy who receive 500 mg curcumin tablets once a day for up to 3 months.. No - There is not a plan to make this available Justification or reason for not sharing IPD is Failure to make a decision
public Fatemeh Rezaie
HAFT BAGH ALAVI
kerman Iran (Islamic Republic of) 7616913555 +98 34 3132 5690 Fatemeh.dsdt4@gmail.com Kerman University of Medical Sciences scientific Fatemeh Rezaie
haft baghe alavi
kerman Iran (Islamic Republic of) 7616913555 +98 34 3132 5690 Fatemeh.dsdt4@gmail.com Kerman University of Medical Sciences Iran (Islamic Republic of) Having symptoms of neuropathy Confirmation of neuropathy by ncv test and doctor's examination no limit no limit Female Cancer patients who have neuropathy caused by factors other than chemotherapy drugs, such as diabetics, pregnant and lactating mothers, people who receive painkillers such as morphine Treatment - Drugs Intervention group: patients with chemotherapy-induced neuropathy who receive 500 mg curcumin tablets once a day for up to 3 months. شدت نوروپاتی (بر اساس آیتم های پرسشنامه) بیمارانی که داروی شیمی درمانی دسته تاکسان ها دریافت میکنند. Timepoint: Evaluation of neuropathy in patients is before the administration of drugs, in the middle of the administration period (45 days after the administration of the interventions i.e. the administration of the first dose of drugs, placebo and positive control) and after the treatment (up to 1 month after the last administration of the interventions). Method of measurement: Nerve conduction speed test, doctor's examination and questionnaire. Kerman University of Medical Sciences Approved 2022-06-05 Research Ethics Committee of Kerman University of Medical Sciences haft bagh alavi kerman Kerman Iran (Islamic Republic of)