IRCT20220502054722N1 IRCT 2022-11-26 Vice-Chancellery for Research, Hormozgan University of Medical Sciences Metoclopramide versus ondansetron for preventing nausea and vomiting after cesarean section Comparing the effect of Metoclopramide and ondansetron for preventing nausea and vomiting after cesarean section 2022-08-22 anticipated 150 Complete https://irct.ir/trial/65020 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Simple randomization with individuals as units of randomization along with allocation concealment: 150 opaque envelopes and 150 cards with the names of the groups (A, B, C) will be prepared (50 cards for each group). The cards will be put into the envelopes, and the envelopes will be sealed and provided to the investigator. Upon entrance of each patient to the study, the envelopes will be shuffled, and one will randomly be selected. The patient will be allocated to groups A, B, or C based on the card inside the selected envelope, Blinding description: Metoclopramide, ondansetron, and normal saline have the same color, and an identical volume of these drugs (10 ml) will be administered. These drugs will be prepared in similar vials by an individual uninvolved in the study. Therefore, the patients, the caregivers, the investigator, and the outcome assessor will be unaware of the injected drug for each patient. 3 Post-operative nausea and vomiting. Intervention 1: Intervention group 1: 5 minutes before spinal anesthesia, intravenous metoclopramide 10 mg/2 ml (DarouPakhsh Co., Iran) diluted with 8 ml normal saline will be injected within 2 minutes. Intervention 2: Intervention group 2: 5 minutes before spinal anesthesia, intravenous ondansetron 4 mg/2 ml (Exir Co., Iran) diluted with 8 ml normal saline will be injected within 2 minutes. Intervention 3: Control group: 5 min before spinal anesthesia, 10 ml normal saline (placebo) will be injected within 2 minutes. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information.