IRCT20220513054837N1 IRCT 2022-09-03 Shiraz University of Medical Sciences comparison of curcuma with meloxicam in knee osteoarthritis pain relief Evaluation of the efficacy of curcuma drug in comparison with meloxicam on pain relief and functional improvement of patients with knee osteoarthritis 2022-08-28 anticipated 60 Complete https://irct.ir/trial/64562 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Factorial, Purpose: Treatment, Randomization description: To make the study random, the blocked and cluster random method is used. Patients also in terms of age and the severity of the symptoms of the disease is divided into categories. The list will be prepared by a computer with the same block length and the secretary of the clinic divides patients based on the list, Blinding description: The blinding of the study is that the statistical expert and the questioner will not know the prescribed Medications to patients, but patients will not be blind in this study. For each patient to separately, first the cause and then the stages of research and the drugs used and their side effects will be explained and a written letter of satisfaction is taken. 3 knee osteoarthritis. Intervention 1: Intervention group: 1, Treatment in group 1 includes taking 15 mg of meloxicam orally daily for ten days and patients will be taught the method of correcting the way of life and Omeprazole will be prescribed also if needed so they take it fasting. Intervention 2: Intervention group: 2, treatment in group 2 will include two turmeric tablets (curcuma longa ) (turmeric extract) daily for one month, each tablet contains 450 mg of turmeric rhizome powder and 50 mg of turmeric extract and patients will be taught the method of correcting the way of life and Omeprazole will be prescribed also if needed so they take it fasting. Yes - There is a plan to make this available What will be shared: all existing data will be reachable after making people unidentifiable When: starting access period one year after publish To whom: all personal Conditions: if data from this study could help improve sciences trend . Where to obtain: alireza karimi 09015613559 How to obtain: after sending request , a call will be made with cooperative personal and if there are no disagreement , requesting data will be send to them in 4 weeks period . Comments: