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IRCT20220625055269N1 IRCT 2023-02-26 Shahed University the effect of Cyperus rotundus herbal oral product on the treatment of mild to moderate Alzheimer disease. The effect of Cyperus rotundus herbal oral product on the treatment of mild to moderate Alzheimer disease. 2023-03-06 anticipated 30 Complete https://irct.ir/trial/64449 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: computer generated list of random numbers (random number generator) random is generated by the statistician by a computer software. The pharmacist numbers the drug containers based on the allocation sequence. The PI enrolls the participants and assigns them to interventions, Blinding description: Drugs and placebos are prepared by a person other than the researcher and colleagues involved in the research in identical containers with the same label, shape and aroma, and the researcher and the patient have no knowledge of the presence of a placebo or real medicine in the medicine package. 1-2 Alzheimer. Intervention 1: The intervention group received capsules containing 250 mg of dried Saad Kofi root powder prepared by Sanabel Pharma Co.Ltd twice a day for 8 weeks. MMSE, FAST, CDR cognitive tests are taken from patients before the study and at the end of the eighth week by standard questionnaires. Before the start of the study and at the end of the fourth and eighth weeks, the patients are visited by a neurologist for free, and whenever necessary, the patients can contact the doctor in charge of the study by phone and ask him from Inform the possible side effects of the drug. Intervention 2: Control group: The control group also received oral capsules containing breadcrumbs made by Sanabel Pharma Co.Ltd twice a day for 8 weeks. No - There is not a plan to make this available Justification or reason for not sharing IPD is In order to comply with the principle of confidentiality and non-disclosure of patients' private and confidential information
public Leila Moein Lashkajani
3rd Dashtestan, pasdaran ave. Tehran, Iran
Tehran Iran (Islamic Republic of) 1947817881 +98 912 299 7633 leilamoein@gmail.com Shahed University scientific Leila Moein Lashkajani
3rd Dshtestan, Pasdaran ave. Tehran. Iran
Tehran Iran (Islamic Republic of) 1947817881 +98 21 2288 2521 leilamoein@gmail.com Shahed University Iran (Islamic Republic of) Male or female over the age of fifty-five with mild to moderate Alzheimer's disease diagnosed by a neurologist according to the NINCDS-ADRDA criteria. 55 years no limit Both major depression Having a congenital cognitive disorder Structural disorders of the brain poor control diabetes G30 Alzheimer's disease Treatment - Drugs Placebo The intervention group received capsules containing 250 mg of dried Saad Kofi root powder prepared by Sanabel Pharma Co.Ltd twice a day for 8 weeks. MMSE, FAST, CDR cognitive tests are taken from patients before the study and at the end of the eighth week by standard questionnaires. Before the start of the study and at the end of the fourth and eighth weeks, the patients are visited by a neurologist for free, and whenever necessary, the patients can contact the doctor in charge of the study by phone and ask him from Inform the possible side effects of the drug. Control group: The control group also received oral capsules containing breadcrumbs made by Sanabel Pharma Co.Ltd twice a day for 8 weeks. Cognitive function. Timepoint: week 0, week 4 and week 8. Method of measurement: MMSE & FAST questionnaire. Brain Mezaj. Timepoint: week 0 and 8. Method of measurement: Fattahi bran Mezaj questioner. Alzheimer severity. Timepoint: week 0 and 8. Method of measurement: clinical dementia rating scale-CDR. Shahed University Approved 2023-01-02 Medical ethic committee of Shahed university Zarafshan ave, Simaye Iran Ave Tehran Tehran Iran (Islamic Republic of)