<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20220620055232N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2022-07-26</date_registration>
      <primary_sponsor>The university of Shahid Beheshti</primary_sponsor>
      <public_title>The Effect of Weightlifting Training with Adding Respiratory Dead Space on Performance and Muscle Hypertrophy</public_title>
      <acronym></acronym>
      <scientific_title>The Effect of Ten Weeks of Weightlifting Training with Adding Respiratory Dead Space on Performance and Muscle Hypertrophy Variables in Young Lifters</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2022-08-23</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>20</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/64351</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Other, Randomization description: First, a list of subjects is prepared according to the inclusion criteria and available sampling, after determining the sample size with G power software, 20 people are selected by simple random method and random digits table. First, each person in the list is given a two-digit code, and then randomly, blindfolded and using a finger, we start from a point in the table of random numbers in the direction of the row or column, and we choose a number that is actually the code of a person from the list. which is chosen as a sample and we place them equally in two groups so that the first code is placed in the first group and the second code is placed in the second group and we continue in the same way until reaching the desired sample size.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Performance and hypertrophy in male weightlifters.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group: exercise group with mask and tube. Using an oxygen mask with a ventilator tube 2.5 cm in diameter and 204 cm long to provide 1000 ml of dead space is used by this group during weightlifting exercises. Intervention 2: Control group: exercise group without mask and tube. This group will do their weightlifting exercises without using masks and tubes.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>No - There is not a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for not sharing IPD is Each person's data alone is useless.</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Vahid Rabiei</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Unit 2, 5th Floor, Danesh pazhohan building of Shahid Beheshti University, Daneshjou Blvd</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1984845497</zip>
        <telephone>+98 21 2243 2257</telephone>
        <email>v_rabiei@sbu.ac.ir</email>
        <affiliation>The University of Shahid Beheshti</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Mohammad Fashi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Faculty of Sport Sciences and health, Shahid Beheshti University, Daneshjou Blvd.</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>11 94 96 83 19</zip>
        <telephone>+98 21 2990 5821</telephone>
        <email>m_fashi@sbu.ac.ir</email>
        <affiliation>The University of Shahid Beheshti</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Weightlifter boys 18 to 25 years old; have a body mass index between 19 to 25 with a body fat percentage of 12 to 15% ; have a history of weightlifting training for at least six months; no history of chronic disease (no diabetes, Blood pressure, chronic lung disease, etc.); no history of smoking for at least the last six months; no musculoskeletal injury or complication; no medication and weight loss program; no special diet; in three months Have not used energizers or anabolic steroids even in therapeutic discussions before starting research exercises.</inclusion_criteria>
      <agemin>18 years</agemin>
      <agemax>25 years</agemax>
      <gender>Male</gender>
      <exclusion_criteria>Musculoskeletal injuries - Infectious and viral diseases of the lungs - Taking any medication without prior notice - Absence of more than one third of training sessions</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code></hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword></hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Other</i_code>
      <i_code>Other</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group: exercise group with mask and tube. Using an oxygen mask with a ventilator tube 2.5 cm in diameter and 204 cm long to provide 1000 ml of dead space is used by this group during weightlifting exercises.</i_keyword>
      <i_keyword>Control group: exercise group without mask and tube. This group will do their weightlifting exercises without using masks and tubes.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Muscle performance. Timepoint: Before the intervention and ten weeks after the intervention (48 hours after the last session). Method of measurement: Using the Biodex isokinetic device, peak torque variables are measured in units of newtons per meter - total work consumed in units of Joules-peak and average power in units of watts.</prim_outcome>
      <prim_outcome>Muscle performance. Timepoint: Before the intervention and ten weeks after the intervention (48 hours after the last session). Method of measurement: It is used to calculate anaerobic power using the Monark ergometer and its unit is watts per kilogram.</prim_outcome>
      <prim_outcome>Muscle Hypertrophy. Timepoint: Before the intervention and ten weeks after the intervention (48 hours after the last session). Method of measurement: MRI will be taken by imaging the cross-section of the muscle from the vastus lateralis muscle of the quadriceps.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>Maximum muscle strength. Timepoint: before the start of the first session and 48 hours after the last training session. Method of measurement: It is calculated by measuring a maximum repetition using the formula: 1RM(Kg) = weight /  1.0278 – (0.0278 × reps ).</sec_outcome>
      <sec_outcome>Maximum rate of oxygen consumption (VO2max). Timepoint: before the start of the first session and 48 hours after the last training. Method of measurement: It will be measured using the Bruce test on a treadmill (H campus) and a respiratory gas analysis device. Its unit is milliliter per kilogram of weight per minute.</sec_outcome>
      <sec_outcome>Serum testosterone concentration. Timepoint: Before and immediately after the first session - before and immediately after the last session - 48 hours after the last session. Method of measurement: It is done by taking blood and measuring with diagnostic kits. Its unit is ng/ml .</sec_outcome>
      <sec_outcome>Serum cortisol concentration. Timepoint: Before and immediately after the first session - before and immediately after the last session - 48 hours after the last session. Method of measurement: It is done by taking blood and measuring with diagnostic kits. Its unit is mg/dl .</sec_outcome>
      <sec_outcome>Serum lactate concentration. Timepoint: Before and immediately after the first session - before and immediately after the last session - 48 hours after the last session. Method of measurement: It is done by taking blood and measuring with diagnostic kits. Its unit is mg/dl .</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>The university of Shahid Beheshti</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2021-11-13</approval_date>
        <contact_name>Research Ethics committees of Shahid Behesh Universityti</contact_name>
        <contact_address>Faculty of Sport Sciences and health, Shahid Beheshti University, Daneshjou Blvd. Tehran Tehran Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
