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IRCT20200825048515N59 IRCT 2022-09-12 Esfahan University of Medical Sciences Evaluation of the effect of injectable dexamethasone on excretion of distal ureteral stones Evaluation of the effect of injectable dexamethasone on the frequency and excretion time of distal ureteral stones 2022-09-21 anticipated 100 Complete https://irct.ir/trial/64093 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: En In this study, 100 eligible patients are randomly selected. For this, the letter A is written on 50 sheets, the letter B is written on 50 sheets, and each is placed in an envelope. Each patient is then asked to choose one of the envelopes. The patient is assigned to one of two groups depending on the selected envelope, Blinding description: In this study, two drugs, dexamethasone, and distilled water, are pre-prepared in similar syringes of the same volume and placed in coded packages, and delivered daily to the researcher. The researcher prescribes each drug without knowing the type. Also, the person recording the patient and clinical information and the statistical analyst will not be aware of the type of intervention. 3 Calculus of ureter. Intervention 1: Intervention group: Patients in this group are treated orally with Tamsulosin 0.4 mg / day for two weeks. In addition, an intramuscular injection of 8 mg dexamethasone will be given. Intervention 2: Control group: Patients in this group receive oral tamsulosin 0.4 mg / day for two weeks. In addition, 8 mg of distilled water will be injected intramuscularly within a week. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information
public Reza Kazemi
Urology Department, Al-Zahra Hospital, Hezar Jerib Street.
Isfahan Iran (Islamic Republic of) 8174675731 +98 31 3620 2020 dr.rezakazemi6788@gmail.com Esfahan University of Medical Sciences scientific Reza Kazemi
Urology Department, Al-Zahra Hospital, Hezar Jerib Street.
Isfahan Iran (Islamic Republic of) 8174675731 +98 31 3620 2020 dr.rezakazemi6788@gmail.com Esfahan University of Medical Sciences Iran (Islamic Republic of) Definitive diagnosis of distal ureteral stones below 1 cm Age over 18 years Indicated for drug therapy Satisfaction to participate in the study 18 years no limit Both Having benign prostatic hyperplasia (BPH) at the same time Having a narrowing of the urethra Contraindications to the use of corticosteroids Existence of hydronephrosis N20.1 Calculus of ureter Treatment - Drugs Placebo Intervention group: Patients in this group are treated orally with Tamsulosin 0.4 mg / day for two weeks. In addition, an intramuscular injection of 8 mg dexamethasone will be given. Control group: Patients in this group receive oral tamsulosin 0.4 mg / day for two weeks. In addition, 8 mg of distilled water will be injected intramuscularly within a week. Frequent distal ureteral stone excretion. Timepoint: Until the end of two weeks of intervention. Method of measurement: Observational. Time to excrete distal ureteral stone. Timepoint: Until the end of two weeks of intervention. Method of measurement: Observational. Isfahan University of Medical Sciences Approved 2021-04-10 Ethics committee of Isfahan University of Medical Sciences Hezar Jarib Ave, Azadi Square. Isfaha Isfehan Iran (Islamic Republic of)