IRCT20220607055095N1 IRCT 2022-06-26 Tehran University of Medical Sciences ٍEffects of Atomoxetine and Trazodone combination in obstructive sleep apnea Evaluating the effects of the Atomoxetine and Trazodone combination on the number of apneas and apnea-hypopnea sleep index in obstructive sleep apnea patients referred to the sleep clinic of Imam Khomeini hospital. 2022-07-06 anticipated 18 Complete https://irct.ir/trial/64022 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Crossover, Purpose: Treatment, Randomization description: In order to randomize, the random block method has been used. In this method, blocks of 4, 6 and 8 are used. Patients are randomly divided into two groups A and B with equal numbers. In the first session, group A receives the placebo half an hour before bedtime and group B receives the study drug half an hour before bedtime, and in the second session, group A receives the study drug half an hour before bedtime and group B receives placebo half an hour before bedtime, Blinding description: The patient does not know in which treatment group he is. The data analyzer does not know about the treatment performed. 2-3 obstructive sleep apnea. Intervention 1: Intervention group: Patients are treated with 80 mg of atomoxetine (Mofid company) and 50 mg of trazodone (Razak company) once half an hour before the polysomnography test and then undergo polysomnography overnight. Intervention 2: Control group: Patients are treated with placebo once half an hour before the polysomnography test and then undergo polysomnography overnight. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information