IRCT20191106045356N11 IRCT 2022-06-30 Yazd University of Medical Sciences Evaluation of the effect of Memantine and Escitalopram combination on Severity of Symptoms and Cognitive Function Among Patients with Obsessive-Compulsive Disorder Evaluation of the effect of Memantine and Escitalopram combination on Severity of Symptoms and Cognitive Function Among Patients with Obsessive-Compulsive Disorder: A double-Blinded Placebo-Controlled, Randomized Clinical Trial 2022-07-21 anticipated 20 Complete https://irct.ir/trial/63519 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization is performed based on the RAND function of Excel software and patients are included in one of the two groups according to the table of random numbers obtained from Excel software, respectively, according to the inclusion criteria. They receive the medication related to their group, which is encoded in uniformly sealed containers. Neither the physician nor the patient intervenes in the selection of the group and they do not know the content of each container of medicine, Blinding description: Drugs and placebo are placed in coded uniform containers, and patients receive one of the containers according to ethical considerations and according to the inclusion criteria and the table of random numbers. Neither the doctor nor the patient knows the medicinal content of each container. 4 Obsessive-Compulsive Disorder. Control group: Memantine treatment. Patients' rates of hospitalization, discharge, depression, and psychosocial functioning were evaluated.. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information.