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IRCT20130507013263N2 IRCT 2022-08-19 Measurement of Crostin serum level after administration of Crocina tablet using HPLC technique Measurement of Crostin serum level after administration of Crocina tablet using HPLC technique 2022-06-05 anticipated 5 Complete https://irct.ir/trial/63365 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Used, Assignment: Parallel, Purpose: Basic scienece. 2 Evaluation of the concentration-time curve of the a Crostin in healthy people. Administration of one crocin tablet made by Samisaz company containing 15 mg of crocin orally.. Yes - There is a plan to make this available What will be shared: - When: Access period starts 6 months after the results are published To whom: Co-worker of proposal. Hossein Kamali and Faezeh Ghorbanzadeh and Mojgan Nejabat Conditions: - Where to obtain: Refer to me Farzin Hadizadeh. contact us: hadizadehf@mums.ac.ir How to obtain: - Comments: -
public Farzin Hadizadeh
School of Pharmacy
Mashhad Iran (Islamic Republic of) 9177948954 +98 51 3180 1128 hadizadehf@mums.ac.ir Mashhad University of Medical Sciences scientific Farzin Hadizadeh
School of Pharmacy
Mashhad Iran (Islamic Republic of) 9177948954 +98 51 3180 1128 hadizadehf@mums.ac.ir Mashhad University of Medical Sciences Iran (Islamic Republic of) Patient willingness to participate in the study Age above 18 years No addiction to narcotics, sedatives and alcohol No history of mental illness, no use of anticoagulants Absence of diabetes Absence of underlying disease 18 years 50 years Male Hemodynamic instability in participant history of Cardiopulmonary resuscitation in participant past medical history of admission in the intensive care unit abnormal liver tests ( AST، ALT، CBC ) abnormal kidney tests ( U/A، BUN، Cr ) Other Administration of one crocin tablet made by Samisaz company containing 15 mg of crocin orally. Determination of crostin blood concentration. Timepoint: Blood sampling will be done at 0, 30, 60, 90, 120, 180 and 240 minutes after drug administration. Method of measurement: Determination of crostin blood concentration by HPLC (High-performance liquid chromatography) system. Mashhad University of Medical Sciences Mashhad University of Medical Sciences Approved 2022-04-09 Ethics committee of Mashhad University of Medical Sciences school of Pharmacy, Mashhad University of Medical Sciences, Azadi Sq., Mashhad Mashhad Razavi Khorasan Iran (Islamic Republic of)