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IRCT20220418054577N1 IRCT 2022-05-14 Private The effect of 12 weeks of continuous training and Interval training on oxidative stress and DNA damage in breast cancer survivors The effect of 12 weeks of continuous training and Interval training on oxidative stress and DNA damage in breast cancer survivors 2022-08-22 anticipated 45 Complete https://irct.ir/trial/63174 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Randomization Method: Simple Randomization, Randomization Unit: Individual, Randomization Tool: Random Number Table. N/A breast cancer. Intervention 1: Intervention group: Medium intensity continuous training: During the research, this group will perform three sessions of moderate intensity continuous training for 12 weeks and a week. All aspects of this study are in line with the basic principles of the Helsinki Declaration. The present study is an applied and quasi-experimental method that is performed in two interventions group and a control group. The statistical population of this study includes 45 postmenopausal women after at least six months of termination of their treatment for breast cancer. After the initial assessments, the subjects are randomly divided into three groups of 15 people with continuous training and interval training and the control group. The subjects of the continuous training are subjected to sports intervention for 12 weeks. Each training session is performed using the Ergometer Monark 894E bicycle for 20-30 minutes and under the full supervision of the instructor and physician. At each training session, subjects' heart rate information is monitored by a Finnish-made Polar heart rate monitor and the exercise pressure perception rate (Borg scale RPE scale 6 to 20) is monitored and recorded regularly throughout the time. Intervention 2: Control group:The control group consists of 15 postmenopausal women who are followed during this period and do not do any sports intervention and only continue their daily activities and routine medical care. Intervention 3: Intervention group: High intensity interval training:During the research, this group will perform three sessions of high-intensity interval training for 12 weeks.All aspects of this study are in accordance with the basic principles of the Declaration of Helsinki. The current research is applied and semi-experimental in two intervention groups and one control group. The statistical population of this research includes 45 menopausal women after at least six months of breast cancer treatment. After the initial evaluations, the subjects are randomly divided into three groups of 15 people: continuous exercise, intermittent exercise group, and control group.Each exercise session is done using an ergometer Monark 894E bicycle for 20-30 minutes under the full supervision of a trainer and doctor. In each training session, the subject's heart rate information is recorded regularly by means of Polar heart rate monitor made in Finland and the level of perception of training pressure (by Borg RPE scale 6 to 20) during the entire monitoring time. The main training in this group is in At first (the first week), there were four training stages (30 seconds of pedaling and 2 active rests) in a row. The number of steps increases every week until it reaches 7 steps in the fourth week (one step was added every week until the fourth week), from the fourth week to the 12th week, the number of steps is maintained at the same number (7 steps). Yes - There is a plan to make this available What will be shared: Patients' personal information is confidential. But access to research methods and information obtained from research is not an obstacle When: Access period starts 6 months after the results are published " To whom: All students and enthusiasts Conditions: To use the data to conduct research in this area Where to obtain: Authors of this article: sahabeh_mahdiann@yahoo.com How to obtain: By sending an email to the author will cooperate with the applicant at the earliest opportunity Comments:
public parisa pournemati
Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, North Kargar St., Iran
Tehran Iran (Islamic Republic of) 1417614418 +98 21 8835 1730 p.pournemati@ut.ac.ir Faculty of Physical Education and Sport Sciences - University of Tehran scientific Parisa pournemati
Faculty of Physical Education and Sport Sciences, University of Tehran, Iran, Tehran, North Kargar St.tehran. iran
Tehran Iran (Islamic Republic of) 1417614418 1417614418 p.pournemati@ut.ac.ir Faculty of Physical Education and Sport Sciences, University of Tehran Iran (Islamic Republic of) at least 6 months of complete discontinuation of breast cancer treatment permission of the physician to participating in the research women should be on the same levele in terms of health،life ، nutrition ،duration of illness body mass index shoul be above 25kg/m2.weight of body fat more than 30% ability to exercise with the approval of an oncologist and cardiologist menopause 54 years 60 years Female Cardiovascular disease Diabetes disease Thyroid disease Smoking C50 Malignant neoplasm of breast Rehabilitation Lifestyle Rehabilitation Intervention group: Medium intensity continuous training: During the research, this group will perform three sessions of moderate intensity continuous training for 12 weeks and a week. All aspects of this study are in line with the basic principles of the Helsinki Declaration. The present study is an applied and quasi-experimental method that is performed in two interventions group and a control group. The statistical population of this study includes 45 postmenopausal women after at least six months of termination of their treatment for breast cancer. After the initial assessments, the subjects are randomly divided into three groups of 15 people with continuous training and interval training and the control group. The subjects of the continuous training are subjected to sports intervention for 12 weeks. Each training session is performed using the Ergometer Monark 894E bicycle for 20-30 minutes and under the full supervision of the instructor and physician. At each training session, subjects' heart rate information is monitored by a Finnish-made Polar heart rate monitor and the exercise pressure perception rate (Borg scale RPE scale 6 to 20) is monitored and recorded regularly throughout the time. Control group:The control group consists of 15 postmenopausal women who are followed during this period and do not do any sports intervention and only continue their daily activities and routine medical care. Intervention group: High intensity interval training:During the research, this group will perform three sessions of high-intensity interval training for 12 weeks.All aspects of this study are in accordance with the basic principles of the Declaration of Helsinki. The current research is applied and semi-experimental in two intervention groups and one control group. The statistical population of this research includes 45 menopausal women after at least six months of breast cancer treatment. After the initial evaluations, the subjects are randomly divided into three groups of 15 people: continuous exercise, intermittent exercise group, and control group.Each exercise session is done using an ergometer Monark 894E bicycle for 20-30 minutes under the full supervision of a trainer and doctor. In each training session, the subject's heart rate information is recorded regularly by means of Polar heart rate monitor made in Finland and the level of perception of training pressure (by Borg RPE scale 6 to 20) during the entire monitoring time. The main training in this group is in At first (the first week), there were four training stages (30 seconds of pedaling and 2 active rests) in a row. The number of steps increases every week until it reaches 7 steps in the fourth week (one step was added every week until the fourth week), from the fourth week to the 12th week, the number of steps is maintained at the same number (7 steps). Serum SOD levels. Timepoint: 48 hours before and after the desired interventions. Method of measurement: Blood sampling using ELISA method. Serum GPX levels. Timepoint: 48 hours before and after the desired interventions. Method of measurement: Blood sampling using ELISA method. Serum TAC levels. Timepoint: 48 hours before and after the desired interventions. Method of measurement: Blood sampling using ELISA method. Serum MDA levels. Timepoint: 48 hours before and after the desired interventions. Method of measurement: Blood sampling using ELISA method. Serum 8-OHdg levels. Timepoint: 48 hours before and after the desired interventions. Method of measurement: Blood sampling using ELISA method. Private Approved 2021-12-19 Ethics Committee of the Institute of Physical Education and Sports Sciences No 3, Fifth Alley, Mir Emad St, Ostad Motahhari St, Tehran tehran Tehran Iran (Islamic Republic of)