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IRCT20220418054585N1 IRCT 2022-07-17 Shahre-kord University of Medical Sciences Comparison effect of Naproxen and Meloxicam after fully occluded mandibular third molar surgery A comparative study of the effect of Meloxicam 7.5 mg and Naproxen 250 mg in reducing complications after fully occluded mandibular third molar surgery;a split-mouth study 2022-05-20 anticipated 30 Complete https://irct.ir/trial/63053 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients will be selected and entered into the study according to the inclusion criteria by simple random sampling. In order to randomly assign individuals to the groups under study, the method of randomization of permutation blocks with a volume of 16 blocks will be used. The randomization list will be prepared by permutation block method using Random allocation software and will be provided to the researcher, Blinding description: This clinical trial study will be performed in a double-blind manner so that blinding will be performed for both patients participating in the study and the statistician. Blinding for patients will be such that naproxen and meloxicam tablets will be available in similar packages and in exactly the same color, and patients will have no knowledge of the content of the intervention received. Also, the information file will be provided to the statistical analyst in the form of groups A and group B, and this person will not have any information about the content of the intervention of groups A and B, which means that all results will be analyzed based on groups A and B and provided to the main researcher. . 3 Extraction of fully occluded mandibular third molar surgery. Intervention group: After the third molar tooth surgery in one side of the mandible, meloxicam 7.5 mg will be prescribed, and after the impacted tooth surgery on the other side of the mandible, naproxen 250 mg. Will be prescribed. In this way, 60 dental surgeries will be evaluated in 30 people.. Yes - There is a plan to make this available What will be shared: Patient information will be provided in the form of tables and graphs while maintaining confidentiality. When: The start of access to information will be after analyzing the information and confirming the scientific references. To whom: Due to the therapeutic role of the study, therapists and researchers will be allowed to access the data. Conditions: Doctors and dentists, statistical consultants of articles, scientific journals can submit applications. Where to obtain: 1)A2022karimi@gmail.com 2)smmoosavis@gmail.com How to obtain: After verifying the identity of the applicant will be provided to them. Comments:
public Ali Karimi
No 91,Kouche bagh, Gol shabbou Blvd,Amirkabir Blvd,
Khmeynishahr Iran (Islamic Republic of) 8437148614 +98 31 3372 4342 a2022karimi@gmail.com Shahre-kord University of Medical Sciences scientific Seyed Masih Mousavi Seresht
Dental school,Resalat Squ
Shahre kord Iran (Islamic Republic of) ۸۸۱۵۷۱۳۴۷۱ +98 38 3232 2400 smmoosavis@gmail.com Shahre-kord University of Medical Sciences Iran (Islamic Republic of) Patients are in the age range of 20 to 35 years Have no history of any systemic disease It also has good oral hygiene Have the consent to enter the study. 20 years 35 years Both Patients who are pregnant, Has a history of drug addiction and analgesics Have used painkillers 24 hours before the operation The root of the impacted tooth is in contact with the mandibular nerve Treatment - Drugs Intervention group: After the third molar tooth surgery in one side of the mandible, meloxicam 7.5 mg will be prescribed, and after the impacted tooth surgery on the other side of the mandible, naproxen 250 mg. Will be prescribed. In this way, 60 dental surgeries will be evaluated in 30 people. Pain. Timepoint: 12 and 24 hours after surgery,. Method of measurement: The Visual Analogue Scale is used to assess pain before surgery, 12 and 24 hours after. This scale includes derivation from zero to 10. Zero means no pain and 10 means too much pain, forcing the person to rest at home. The patient will be informed about the pain scale before surgery and will be asked by phone 12 and 24 hours after surgery. Swelling. Timepoint: 2 and 7 days after surgery. Method of measurement: . To evaluate swelling before surgery, 2 and 7 days later, Gabka and Matsura methods are used. will be. In this method, the distance between the outer corner of the eye and the mandibular angle, between the tragus and the outer corner of the mouth, and between the tragus and the soft tissue of the pogunion is measured in millimeters. Then the average of these three numbers is calculated and inflation is obtained. Trismus. Timepoint: 2 and 7 days after surgery. Method of measurement: A ruler will be used to check for trismus before surgery, 2 and 7 days after. The distances between the upper and lower centers before and after the operation are measured using a ruler. Shahre-kord University of Medical Sciences Approved 2022-07-05 Ethics committee of Shahrekord University of Medical Sciences kashani Blvd , Shahrekord Sharekord Chahar-Mahal-va-Bakhtiari Iran (Islamic Republic of)