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IRCT20220414054533N1 IRCT 2022-10-22 Qazvin University of Medical Sciences Evaluation of wound healing in two methods of silver ointment and coriander oil in patients with second degree burns Evaluation of wound healing in two methods of silver ointment and coriander oil in patients with second degree burns 2022-06-22 anticipated 66 Complete https://irct.ir/trial/62961 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients are assigned to two treatment groups A and B using the balanced block randomization method through https://www.sealedenvelope.com/simple-randomiser/v1/lists. The size of each block is 6 and the total number of blocks is 11 . Balanced randomization allocation for the participants in the current study, the effect of silver sulfadiazine ointment 1% (A) and beneh oil (B) on wound healing is investigated, Blinding description: Checklist information is provided by the secretary of the department in which people with national code are registered to the person responsible for the analysis and statistical analysis of the plan. After entering SPSS and coding 1 and 2, the results of the evaluation will be analyzed by the professor of statistics, separated into intervention and control groups (which only the secretary of the department knows about). and the professor of statistics is not aware of which medicinal ointment the patient received. The data analyst and the safety monitoring committee are not aware of which drugs the patients took. 0 (exploratory trials) burning. Intervention 1: Intervention group: in the second group with 33 patients, coriander oil at the rate of 200 mg once a day is prescribed to be applied on the burned areas. In this way, after rinsing with normal saline serum, the wound is placed in the presence of air for 5 minutes to dry, and then a thin layer is spread on the wound with a sterile swab and a light dressing of sterile gas is placed on it. Wound dressings are changed daily until the wound heals. Intervention 2: Control group: in the first treatment group with 33 patients, 1% silver cesulfadiazine ointment at a dose of 200 mg per day. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Satisfaction of participants
public Unes Ehsanollahy
Bahonar street
Qazvin Iran (Islamic Republic of) 34197-59811 +98 28 3333 6001 dr.y.ehsanollahy@gmail.com Qazvin University of Medical Sciences scientific Unes Ehsanollahy
Bahonar street
Qazvin Iran (Islamic Republic of) 34197-58911 +98 28 3333 6001 dr.y.ehsanollay@gmail.com Qazvin University of Medical Sciences Iran (Islamic Republic of) All patients who come to the hospital with a second-degree burn 2 years 60 years Both Children People who do not agree to participate in this study People with underlying diseases of diabetes Immunodeficiency or use immunosuppressive drugs T31.1 Burns involving 10-19% of body surface Treatment - Drugs Treatment - Drugs Intervention group: in the second group with 33 patients, coriander oil at the rate of 200 mg once a day is prescribed to be applied on the burned areas. In this way, after rinsing with normal saline serum, the wound is placed in the presence of air for 5 minutes to dry, and then a thin layer is spread on the wound with a sterile swab and a light dressing of sterile gas is placed on it. Wound dressings are changed daily until the wound heals. Control group: in the first treatment group with 33 patients, 1% silver cesulfadiazine ointment at a dose of 200 mg per day Epithelization of the tissues. Timepoint: Every seven days. Method of measurement: Complete wound closure visually. Time to complete burn wound healing. Timepoint: Every 7 days. Method of measurement: Based on ocular criteria. Qazvin University of Medical Sciences Approved 2021-10-17 Ethics committee of qazvin University of Medical Sciences Rajaei Hospital. Qazvin Qazvin Qazvin Iran (Islamic Republic of)