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IRCT20210711051842N1 IRCT 2022-04-30 Mashhad University of Medical Sciences Effect of pentoxifylline in treatment of patients with slow flow coronary arteries Evaluation of the effect of oral pentoxifylline on reducing chest pain in ischemic patients with slow flow coronary arteries 2022-04-09 anticipated 40 Complete https://irct.ir/trial/62848 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Other, Purpose: Treatment. 2 Pentoxifylline in patients with slow flow coronary arteries. Intervention group: patients with slow flow coronary arteries in angiography will be treated with standard medicine for two weeks and in case of pain continuation, will be treated with oral pentoxifylline 400 milligram three times a day for two weeks and finally pentoxifylline effect in chest pain reduction will be evaluated.( the same questionnaire will be filled two weeks and one month after coronary angiography by the same person). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is after completing and publishing of article in order to opinion of head of study and collagenous will decide .

public Reza Teimouri Dastjerdan

First floor; No.44, Haft-e-tir 15; Haft-e-tir Blvd

Mashhad Iran (Islamic Republic of) 9178854453 +98 51 3867 9747 teimouridr971@mums.ac.ir Mashhad University of Medical Sciences scientific Reza Teimouri Dastjerdan

First floor; No.44, Haft-e-tir 15; Haft-e-tir Blvd

Mashhad Iran (Islamic Republic of) 9178854453 +98 51 3867 9747 teimouridr971@mums.ac.ir Mashhad University of Medical Sciences Iran (Islamic Republic of) Patients with slow flow coronary arteries in angiography 30 years no limit Both Age more than thirty years Creatinine clearance less than 30 Severe aortic stenosis Severe mitral stenosis Treatment - Drugs Intervention group: patients with slow flow coronary arteries in angiography will be treated with standard medicine for two weeks and in case of pain continuation, will be treated with oral pentoxifylline 400 milligram three times a day for two weeks and finally pentoxifylline effect in chest pain reduction will be evaluated.( the same questionnaire will be filled two weeks and one month after coronary angiography by the same person) Severity of chest pain through Likert scale. Timepoint: Evaluation of chest pain after angiography and after two weeks and one month. Method of measurement: Questionnarie for evaluating severity,frequency and duration of chest pain. Frequency chest pain. Timepoint: at the time of angiography and two weeks and one month later. Method of measurement: Questionnaire usage. Duration of chest pain. Timepoint: at the time of angiography and two weeks and one month later. Method of measurement: Questionnaire usage. Severity of chest pain based on Canadian cardiovascular society score (CCS). Timepoint: at the time of angiography and two weeks and one month later. Method of measurement: Questionnaire usage. Mashhad University of Medical Sciences Approved 2021-06-01 Ethics committee of Mashhad University of Medical Sciences First floor; No.44, Haft-e-tir 15; Haft-e-tir Blvd Mashhad Razavi Khorasan Iran (Islamic Republic of)