IRCT20220102053602N1 IRCT 2022-03-16 Gorgan University of Medical Sciences Evaluation of Effectiveness of Oral and Vaginal Misoprostol Administration for Cervical Ripening in Women Before Operative Hysteroscopy Evaluation of Effectiveness of Oral and Vaginal Misoprostol Administration for Cervical Ripening in Women Before Operative Hysteroscopy: A Double-Blind Randomized Placebo Controlled Clinical Trial 2022-04-04 anticipated 126 Complete https://irct.ir/trial/62420 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: To perform randomization in the samples, we use the block method with six blocks. From the following blocks, we first select one at random and divide the samples into 3 groups according to the order. (A for the vaginal group and B for the oral group and C for the placebo group) C C B B A A 1 A C C B B A 2 A A C C B B 3 B A A C C B 4 B B A A C C 5 C A A B B C 6, Blinding description: All patients and physicians evaluating the interventions designed in the study or the consequences after the procedure (gynecology assistant and gynecological laparoscopic surgery fellowship) will not be aware of the group in which the patient is being examined. All interventions in all three groups will be designed similarly and the process will be the same on all samples in all groups. 3 Cervical Ripening. Intervention 1: Intervention group: Misoprostol 400 micrograms tablets vaginally (2 pieces 200 micrograms, Samisaz pharmaceutical company, Iran ) and B6 tablets orally (2 pieces, Aminpharma company, Iran ). Intervention 2: Intervention group: B6 tablets vaginally (2 pieces) and misoprostol 400 mg tablets orally (2 pieces of 200 micrograms). Intervention 3: Control group: B6 tablets orally and B6 tablets vaginally (two each). Yes - There is a plan to make this available What will be shared: Only part of the data, such as information about the main outcome or the like, can be shared. When: Start of access period 6 months after printing results To whom: It will be available to researchers working in academic and scientific institutions. Conditions: Use of data to complete the research process on the effects of oral and vaginal misoprostol on cervical preparation in hysteroscopic women Where to obtain: Contact the author of the article responsible for the research project data. How to obtain: Contact the author of the article responsible for the research project data.Specify the type of results requested. Comments: