IRCT20220110053681N1 IRCT 2022-03-27 Sabzevar University of Medical Sciences Effect of Sertraline in treatment of Covid-19 Evaluation of the Effects of Sertraline on the Prognosis of Patients with Covid - 19 Admitted to Hospital 2022-04-21 anticipated 60 Complete https://irct.ir/trial/62284 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: This project, which is actually a clinical trial, aims to investigate the effects of sertraline on the prognosis of patients with Covid-19, which requires hospitalization depending on the patient's clinical condition, PCR and CT scan results, or clinical diagnosis. In the hospital, patients are divided into intervention and control groups based on permutation block, Blinding description: Because the patient is not asked to evaluate the consequences of the plan and is judged based on the patient's clinical examinations, patient blindness is not required. Only the evaluator of the results should be blindfolded. To do this, another person is used who is unfamiliar with the treatment process and the type of treatment received by the two groups. 3 Covid-19. Intervention 1: Intervention group: This group receives 50 mg daily dose of sertraline with standard treatment including corticosteroids + anticoagulants + Remdesivir during hospitalization. Intervention 2: Control group: This group receives the main treatment regimen during the hospital stay, which includes corticosteroids + anticoagulants + Remdesivir . Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information