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IRCT20220302054168N1 IRCT 2022-03-03 Iran University of Medical Sciences The effect of hydrocolloid dressing in the treatment of skin graft wounds Evaluation of the effectiveness of silver-containing hydrocolloid dressings in the treatment of donor wounds of partial- thickness skin grafts 2022-03-21 anticipated 30 Complete https://irct.ir/trial/62270 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study, we use the block randomization method so that after selecting patients according to the inclusion and exclusion criteria by selecting numbers from the table of random numbers and adapting to the blocks, patients are divided into study groups. To randomize the two treatment methods, we create 4 blocks in six different states, then select a number using the table of numbers, and determine the study groups by matching the numbers with the blocks. For example, if the first digit of our number is 1 to 6, select a block and the division is done, but if, for example, our number is 94071, the digit 9 is not valid and we select the next digit. Here, based on the block 4, we divide patients into groups. 1. TTCC 2. TCTC 3. TCCT 4. CCTT 5. CTCT 6. CTTC, Blinding description: In this study, people who are responsible for patient care and analysis of statistical data do not know about the treatment process and study groups, and information is provided to them in groups A and B. 3 Patients with skin defects. Intervention 1: Intervention group: First, the partial- thickness skin grafts removed with an electric dermatome.The location of the donor, the thickness of the skin removed, and the dimensions of the skin removed are recorded for each patient. Donor injection is not performed at the donor site before removal.The donor site is then covered with epinephrine-impregnated gas at 1 in 100,000 until proper homeostasis is established. In the next step, the donor site is done with Aquacel Ag dressing made by ConvaTec company with dimensions of 15 by 15 cm or 20 by 30 cm, depending on the dimensions of the wound and according to the manufacturer's instructions, then one or two layers of dry gas are placed on this dressing and Finally, the crepe bandage is done. Intervention 2: Control group: First, the partial- thickness skin grafts removed with an electric dermatome.The location of the donor, the thickness of the skin removed, and the dimensions of the skin removed are recorded for each patient. Donor injection is not performed at the donor site before removal.The donor site is then covered with epinephrine-impregnated gas at 1 in 100,000 until proper homeostasis is established. In the next step, the donor site is first placed on the wound with a gas soaked in Vaseline and then bandaged with one or two layers of dry gas and a crepe bandage. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information
public AmirAli Mirfakhraei
Hemmat Highway next to Milad Tower, Iran University of Medical Sciences
Tehran Iran (Islamic Republic of) 1449614535 +98 21 8871 7272 Dr.mirfakhraee@gmail.com Iran University of Medical Sciences scientific AmirAli Mirfakhraei
Hemmat Highway next to Milad Tower, Iran University of Medical Sciences
Tehran Iran (Islamic Republic of) 1449614535 +98 21 8871 7272 Dr.mirfakhraee@gmail.com Iran University of Medical Sciences Iran (Islamic Republic of) Patients who need partial partial- thickness skin grafts to repair skin defects for various reasons 18 years no limit Both Patients who do not wish to participate in the study Patients with previously known allergies to silver A66.2 Other early skin lesions of yaws Treatment - Devices Treatment - Devices Intervention group: First, the partial- thickness skin grafts removed with an electric dermatome.The location of the donor, the thickness of the skin removed, and the dimensions of the skin removed are recorded for each patient. Donor injection is not performed at the donor site before removal.The donor site is then covered with epinephrine-impregnated gas at 1 in 100,000 until proper homeostasis is established. In the next step, the donor site is done with Aquacel Ag dressing made by ConvaTec company with dimensions of 15 by 15 cm or 20 by 30 cm, depending on the dimensions of the wound and according to the manufacturer's instructions, then one or two layers of dry gas are placed on this dressing and Finally, the crepe bandage is done. Control group: First, the partial- thickness skin grafts removed with an electric dermatome.The location of the donor, the thickness of the skin removed, and the dimensions of the skin removed are recorded for each patient. Donor injection is not performed at the donor site before removal.The donor site is then covered with epinephrine-impregnated gas at 1 in 100,000 until proper homeostasis is established. In the next step, the donor site is first placed on the wound with a gas soaked in Vaseline and then bandaged with one or two layers of dry gas and a crepe bandage. The degree of adhesion of the dressing to the wound bed. Timepoint: After dressing the wound up to 14 days after dressing. Method of measurement: Standard checklist. Wound infection. Timepoint: After dressing the wound up to 14 days after dressing. Method of measurement: Standard checklist. Wound healing process. Timepoint: After dressing the wound up to 14 days after dressing. Method of measurement: Standard checklist. Iran University of Medical Sciences Approved 2022-02-08 Ethics committee of Iran University of Medical Sciences Hemmat Highway next to Milad Tower, Iran University of Medical Sciences Tehran Tehran Iran (Islamic Republic of)