IRCT20200504047298N4 IRCT 2022-03-05 Tehran University of Medical Sciences Investigating the effectiveness of Ozone Hemotherapy on the respiratory condition of patients Comparison of the Effectiveness of Ozone Hemotherapy on the Respiratory Condition of Patients with Sever Covid with the Control Group 2022-03-15 anticipated 60 Complete https://irct.ir/trial/62111 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Due to the total sample size, 60 people will be used to maintain the balance between the two groups in random blocking methods. Therefore, 10 blocks of 6 will be formed, and in each block, three in the intervention group and three will be in the control group. Allocating individuals to each block uses random numbers table (from top to bottom). The blinding is in the form of Open Label, that means patients will be informed of their groups, Blinding description: It is open label, meaning that, patients will be informed of their groups. 3 Covid 19. Intervention 1: 30 patients are undergoing Hemotherapy with ozone for 10 sessions. The patient’s blood was taken at the first session to the amount of 120 cc and it is combined with 120 cc of gas. While from the second session, the amount of 240 cc in the blood bag was taken, and it combines with 240 cc ozone gas and it injects back into the patient. The first four sessions are daily, but from the fifth session, it is performed in the form of every other day. Intervention 2: Control group: 30 patients with nearly similar conditions of the intervention group however only receive standard treatment. Yes - There is a plan to make this available What will be shared: Article When: 1402 To whom: researchers Conditions: - Where to obtain: - How to obtain: - Comments: