IRCT20220213054013N1 IRCT 2022-03-09 Esfahan University of Medical Sciences Evaluation of the effectiveness of IVIg therapy on Covid 19 patients. Evaluation of the effectiveness of IVIg therapy on blood (WBC، lymphocyte count), renal (Cr, urea) and liver parameters (AST, ALT) in COVID-19 patients before and after IVIg therapy. 2022-03-01 anticipated 196 Complete https://irct.ir/trial/61934 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Coronavirus (Covid-19). Intervention 1: "Intervention group": In this study, patients with severe type or severity of COVID-19 disease, in addition to other treatments and according to the doctor, had a dose of IVIg treatment, will be included in the study. To eliminate confounders, the control group is used for adaptation and the patients in the control group will be selected almost similar to the study group in terms of sex and age. The results of hematological, hepatic and renal parameters before IVIg injection will be compared with the results of the fourth day after IVIG and will be analyzed. Intervention 2: "Control group": In this study, the control group of patients with severe or severity of COVID-19 disease who receive other therapies of the intervention group except IVIg will be included in the study. This work is used to eliminate confounding factors and for fitting, and patients in the control group will be selected almost similar to the study group in terms of sex and age. The results of hematological, hepatic and renal parameters before IVIg injection will be compared with the results of the fourth day after IVIG and will be analyzed. Yes - There is a plan to make this available What will be shared: The results of tests and clinical findings of patients will be presented in the article after the publication of the article. When: 6 months later To whom: Fields of the Department of Medical Sciences and scientists in this field Conditions: To use or not to use this type of treatment according to the results Where to obtain: Use the extracted article or request it from Behrooz Ghezelbash via email. behroozghezelbash@med.mui.ac.ir How to obtain: By prior arrangement and sending email Comments: