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IRCT20220122053799N1 IRCT 2022-03-05 Tabriz University of Medical Sciences Fabrication and evaluation of the effect of lavender gum in the mouth Fabrication and clinical study of the effect of lavender chewing gum on salivary Streptococcus mutans, salivary pH, plaque index, and gingival bleeding 2022-04-03 anticipated 54 Complete https://irct.ir/trial/61648 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: The study will be conducted randomly among the staff of Tabriz University of Medical Sciences. The method of randomization is simple and its unit is individual. Randomization will be performed in such a way that the first group is identified by code A (intervention) and the second group by code B (control) and will be placed inside sealed envelopes; The envelopes are then placed in a bag and shaken. After returning to the place, people put their hands inside the bag and randomly take out an envelope. After viewing the code, the treatment will be given to the patient. The evaluator and participant are not aware of the type of groups, Blinding description: The present study is two-way blind and the outcome assessor, data analyst, and study participant are not aware of the type of groups. The researcher and outcome assessors are not aware of the randomization and segmentation of the Chewing gums among the participants and do not intervene. To blind the participants to the taste of chewing gum, the same flavoring is added to both types of chewing gum. 2 Dental caries. Intervention 1: Intervention group: Chewing lavender gum by extracting the plant by percolation method using 70% ethanol made in Tabriz Medical Research Center. The amount of gum used per person is six pieces of chewing gum daily, one after each meal and three pieces during The day will be for at least 15 minutes for 14 consecutive days. Intervention 2: Control group: Chewing gum without lavender extract, which is made in Tabriz Medical Research Center. The amount of chewing gum used by each person daily will be six pieces of chewing gum, one after each meal and three pieces during the day for at least 15 minutes for 14 consecutive days. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information
public Maryam Kooh Soltani
Tabriz, Daneshgah St., at the end of Golgasht St.
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 3335 5965 mkoohsoltani@yahoo.com Tabriz University of Medical Sciences scientific Maryam Kooh Soltani
Tabriz, Daneshgah St., at the end of Golgasht St.
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 3335 5965 mkoohsoltani@yahoo.com Tabriz University of Medical Sciences Iran (Islamic Republic of) Participants do not have systemic disease Have acceptable oral hygiene (no clear mass and plaque) Age range 18 to 65 years Do not be pregnant or breastfeeding Having an average of 22 teeth 18 years 65 years Both Taking antibiotics or drugs that affect saliva Use oral appliance Smoking and alcohol consumption People with temporomandibular joint problems K02.3 Arrested dental caries Treatment - Other Placebo Intervention group: Chewing lavender gum by extracting the plant by percolation method using 70% ethanol made in Tabriz Medical Research Center. The amount of gum used per person is six pieces of chewing gum daily, one after each meal and three pieces during The day will be for at least 15 minutes for 14 consecutive days. Control group: Chewing gum without lavender extract, which is made in Tabriz Medical Research Center. The amount of chewing gum used by each person daily will be six pieces of chewing gum, one after each meal and three pieces during the day for at least 15 minutes for 14 consecutive days. Gingival bleeding rate. Timepoint: Measure the percentage of plaque index at the beginning of the study (before the intervention) and 14 days after the start of chewing gum. Method of measurement: Bleeding index using periodontal prop in Salcus at four levels (labial, Lingual and Interproximal). Check the percentage of license plate index. Timepoint: Measure the percentage of plaque index at the beginning of the study (before the intervention) and 14 days after the start of chewing gum. Method of measurement: Plaque detector tablets. Measurement of the number of Streptococcus mutans saliva colonies. Timepoint: Measure the percentage of plaque index at the beginning of the study (before the intervention) and 14 days after the start of chewing gum. Method of measurement: The patient will be asked to collect saliva in the mouth for one minute and then pour it into a sterile Falcon graduated tube. To determine the number of Streptococcus mutans colonies, they should be sent to the microbiology laboratory and incubated in the specific medium of Mitis salivarius agar at 37 ° for 2 days and Streptococcus mutans were counted. Saliva pH. Timepoint: Measure the percentage of plaque index at the beginning of the study (before the intervention) and 14 days after the start of chewing gum. Method of measurement: PH meter. Tabriz University of Medical Sciences Approved 2022-01-12 Ethics committee of Tabriz University of Medical Sciences No. 47, East 4th Floor, Mehdian Alley, Azari St., Valiasr Intersection, Tabriz Town Tabriz East Azarbaijan Iran (Islamic Republic of)