]>
IRCT20081110001444N7 IRCT 2022-02-24 Yazd University of Medical Sciences Evaluation of Direct-Acting Antiviral (DAA) Regimens on hepatitis C. Evaluation of the Effectiveness of Direct-Acting Antiviral (DAA) Regimens in Patients with Hepatitis C: A Multicenter and Follow-up Analysis 2021-12-30 anticipated 51 Complete https://irct.ir/trial/60886 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. 3 Hepatitis C. Intervention group: In this study, therapeutic DAA regimen prescribed for the treatment of the patients with GT3 virus was SOF 400 mg + DCV 60 mg.For the other GT cases, it was SOF 400 mg + LDV 90. According to the recommended instructions, the drugs were taken on an outpatient basis every day.Twelve weeks after the completion of the DAA treatment, the RNA levels of serum HCV were analyzed separately in different GTs using PCR.. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information.
public Mohsen Akhondi Meybodi
Shahid Sadoughi Hospital, Ebne- Sina Ave., Yazd, Iran
Yazd Iran (Islamic Republic of) 8915887857 +98 35 3822 4000 akhondei@yahoo.com Yazd University of Medical Sciences scientific Mohsen Akhondi Meybodi
Shahid Sadoughi University, Ebne-Sina Ave., Yazd, Iran
Yazd Iran (Islamic Republic of) 8915887857 +98 35 3822 4000 akhondei@yahoo.com Yazd University of Medical Sciences Iran (Islamic Republic of) Adults (≥ 18 years) regardless of their previous treatment or stage of liver fibrosis 18 years no limit Both The patients who took drugs including carbamazepine, phenytoin, rifampin, phenobarbital, antacids and rosuvastatin had a history of taking amiodarone in the past three months those with severe renal insufficiency pregnant women patients with no high life expectancy due to other diseases B18.2 Chronic viral hepatitis C Treatment - Drugs Intervention group: In this study, therapeutic DAA regimen prescribed for the treatment of the patients with GT3 virus was SOF 400 mg + DCV 60 mg.For the other GT cases, it was SOF 400 mg + LDV 90. According to the recommended instructions, the drugs were taken on an outpatient basis every day.Twelve weeks after the completion of the DAA treatment, the RNA levels of serum HCV were analyzed separately in different GTs using PCR. Sustained virological response. Timepoint: After 12 weeks. Method of measurement: Polymerase Chain Reaction (PCR). Yazd University of Medical Sciences Approved 2019-01-27 Ethics committee of Yazd Shahid Sadoughi University of Medical Sciences School of Medicine, Shahid Sadoughi University of Medical Sciences, Shohaday-e- Gomnam Blvd., Alem Sq., Yazd, Iran Yazd Yazd Iran (Islamic Republic of)