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IRCT20170620034666N5 IRCT 2022-03-16 Esfahan University of Medical Sciences The effect of cardioplegia on paradoxical septal motion psm The Comparison of the effect of Antegrade and Antegrade-Retrograde blood cardioplegia approach on paradoxical septal motion after coronary artery bypass graft 2021-06-05 anticipated 72 Complete https://irct.ir/trial/60758 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Other design features: This study is performed on two groups and each group has 36 people. In one group, cardioplegia was injected as antegrade and in the other group as antegrade-retrograde and its effects were compared, Randomization description: The simple randomization method was performed by tossing coins between the samples that met the inclusion criteria, considering that there were two groups in the study, Blinding description: The samples did not know the type of implantation of the cardioplegia cannula Caregivers did not know how to insert a cardioplegia cannula The echocardiographer did not know the surgical procedure and the type of cannula implantation. N/A Coronary artery disease. Intervention 1: Intervention group: Intervention group: In one group, cardioplegia cannula is inserted by the surgeon in the root of the aorta and the perfusionist injects the cardioplegia through the heart and lung pump.After surgery and before discharge,paradoxical motion of the septum, which is a measure of myocardial protection, are examined by echocardiography. Intervention 2: Intervention group: In the other group, the cardioplegia solution is injected both in the aortic root and through the coronary sinus, which is implanted by a surgeon with a special device, by a perfusionist through a heart and lung pump as in the previous group, and after surgery and before discharge paradoxical motion of The septum is identified by echocardiography. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information
public Dr mehran shahzamani
Hezar jerib st,esfahan university of medical sciences
Esfahan Iran (Islamic Republic of) 8174673461 031-3668048 M.shahzamani@med.mui.ac.ir Esfahan University of Medical Sciences scientific Dr mehran shahzamani
Hezar jerib st esfahan university of medical sciences
Esfahan Iran (Islamic Republic of) 8174673461 +98 31 3668 0048 Alij1367@gmail.com Esfahan University of Medical Sciences Iran (Islamic Republic of) Being 45 to 65 years old EF more than 50% in preoperative echocardiography No septal movement disorder in preoperative echocardiography No history of myocardial infarction No aortic valve insufficiency in preoperative echocardiography Lack of internal heart pacemaker No absence of right or left branch block in the ECG after cardiac surgery Absence of intraventricular conduction delay (IVCD) in preoperative ECG 45 years 65 years Both The unwillingness of the patient or companions to participate in the study Existence of shunt inside the heart The presence of right and left branch blocks in the ECG before surgery T82.21 Mechanical complication of coronary artery bypass graft Diagnosis Diagnosis Intervention group: Intervention group: In one group, cardioplegia cannula is inserted by the surgeon in the root of the aorta and the perfusionist injects the cardioplegia through the heart and lung pump.After surgery and before discharge,paradoxical motion of the septum, which is a measure of myocardial protection, are examined by echocardiography. Intervention group: In the other group, the cardioplegia solution is injected both in the aortic root and through the coronary sinus, which is implanted by a surgeon with a special device, by a perfusionist through a heart and lung pump as in the previous group, and after surgery and before discharge paradoxical motion of The septum is identified by echocardiography. Paradoxical septal motion. Timepoint: Post surgery. Method of measurement: Echocardiography in M mode. Esfahan University of Medical Sciences Approved 2021-09-20 Isfahan University of Medical Sciences - Committee on Research Ethics Hezar jerib st esfahan university of medical sciences Esfahan Isfehan Iran (Islamic Republic of)