]>
IRCT20211214053407N1 IRCT 2021-12-28 Faculty of Physical Education and Sport Sciences, Shahid Beheshti University, Tehran The effect of exercise on fatigue in MS The Effect of Aerobic-cognitive Combined Training on Inflammatory factors and Mental fatigue in Multiple Sclerosis Patients 2022-01-01 anticipated 45 Complete https://irct.ir/trial/60731 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Participants in this study will be divided into 3 groups of aerobic-cognitive training, aerobic training, and control by simple randomization method and by throwing baldness. The division is such that the names of all the candidates will be written on a piece of paper and the names of each bald person will be placed in front of it. 5 and 6 are also considered for the division of the control group. It should also be noted that if the quorum of each group reaches the quorum, the numbers belonging to that group will be awarded equally to the other two groups. For example, if 14 people in the first group are completed, the number 1 will be assigned to the second group and the number 2 to the third group, and henceforth the numbers 1, 3, and 4 for the second group and the numbers 2, 5 and 6 will be for the third one. N/A Multiple sclerosis. Intervention 1: Intervention group 1: Performing 8 weeks of aerobic-cognitive training called Brightonic training, which includes 2 sessions of approximately 40 minutes each week. Intervention 2: Intervention group 2: Perform 8 weeks of aerobic exercise called isotonic exercise, which includes 2 sessions of approximately 40 minutes each week. Intervention 3: Control group: 8 weeks without any activity and exercise. Yes - There is a plan to make this available What will be shared: Plasma levels of interleukin-17 and interleukin-4 and mental fatigue Some of the data that will be related to the main consequences of the work will be shared after the people are not identified. When: Access period starts 1 year before the results are published To whom: Researchers related to MS Conditions: To study in patients with multiple sclerosis Where to obtain: 1. Department of Sports Physiology, Faculty of Physical Education and Sport Sciences, Shahid Beheshti University, Tehran 2. MS Clinic of Imam Hossein Hospital, Tehran How to obtain: 1. Request via email Dr. Rana Fayyaz Milani 2. Request via e-mail Dr. Mehran Ghaffari Comments:
public Sara Farajnia
Tehran - Saadat Abad - Mohammad Ali Keshavarz Boulevard - East East Corner - No. 35 - Viva Yuka Tower - West West Unit
Tehran Iran (Islamic Republic of) 1997776452 +98 21 2641 6337 sfarajnia2020@gmail.com Faculty of Physical Education and Sport Sciences, Shahid Beheshti University, Tehran scientific Sara Farajnia
Saadat Abad District, Mohammad Ali Keshavarz Blvd., East 2nd Corner, No. 35, Viva Yuka Tower, West First Unit
Tehran Iran (Islamic Republic of) 1997776452 +98 21 2641 6337 sfarajnia2020@gmail.com Shahid Beheshti University of Medical Sciences Iran (Islamic Republic of) The subjects used in this study will be patients with MS and all of them will use interferon. People with recurrent and clinically stable MS with a minimum of disability (EDSS) below 3 will be selected for this study. The age range of the subjects will be 20 to 50 years (based on the average age of the patients). 20 years 50 years Both People with cardiovascular disease, diabetes, thyroid disorders, gout, and orthopedic restrictions Patients who have an attack 4 weeks before or during the project. No signing the consent form approved by the Research Ethics Committee G35 Multiple sclerosis N/A N/A N/A Intervention group 1: Performing 8 weeks of aerobic-cognitive training called Brightonic training, which includes 2 sessions of approximately 40 minutes each week. Intervention group 2: Perform 8 weeks of aerobic exercise called isotonic exercise, which includes 2 sessions of approximately 40 minutes each week. Control group: 8 weeks without any activity and exercise. Determining the effect of Brightonic training on mental fatigue in patients with MS. Timepoint: Pre-test and post-test. Method of measurement: Mental fatigue will be assessed by the MFIS Modified Fatigue Effect Questionnaire. Determining the effect of Brightonic training on inflammatory factors in patients with MS. Timepoint: Pre-test and post-test. Method of measurement: Inflammatory factors will be assessed by measuring the plasma levels of interleukin 17 and interleukin 4 and their ratios. Determining the effect of Brightonic training on sleep quality in patients with MS. Timepoint: Pre-test and post-test. Method of measurement: By the Petersburg Sleep Quality Questionnaire. Determining the effect of Brightonic training on quality of life in patients with MS. Timepoint: Pre-test and post-test. Method of measurement: By Vickery Quality of Life Questionnaire. Faculty of Physical Education and Sport Sciences, Shahid Beheshti University, Tehran Approved 2021-12-19 National Committee for Ethics in Biomedical Research Ghods Town (West) - Between South Flamek and Zarafshan, Iran TV Street - Headquarters of the Ministry of Health, Treatment and Medical Education, Block A, 13th Floor Tehran Tehran Iran (Islamic Republic of)