IRCT201403155623N17 IRCT 2014-03-25 Kashan University of Medical Sciences Effect of supplementation in treatment of cervical intraepithelial neoplasia 1 The effect of folate supplementation on treatment, metabolic profiles and hs-CRP in women with cervical intraepithelial neoplasia 1(CIN1) 2013-09-27 anticipated 58 Complete https://irct.ir/trial/6047 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: At study baseline and after stratification for pre-intervention BMI and age, subjects will be randomly divided into two groups to take either folate supplements (n = 29) or placebo (n = 29). Randomization will be done by the use of computer-generated random numbers, Blinding description: Randomization and allocation will be concealed from the researchers and participants until the final analyses are completed. Another person at the Oncology Clinic at the Kashan University of Medical Sciences, who is not involved in the trial and not aware of random sequences, will be assigned the participants to the numbered bottles of capsules. 2-3 Cervical intraepithelial neoplasia 1(CIN1). Intervention 1: Intervention group: Folic acid tablet, 5 mg, daily, for 6 months orally. Intervention 2: Control group: Placebo tablet, daily, for 6 months orally. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Undecided - It is not yet known if there will be a plan to make this available.