]>
IRCT20190717044255N3 IRCT 2021-11-29 Arak University of Medical Sciences The effect of systemic anticoagulants in repairing penetrating upper limb arterial trauma Investigating the effect of systemic anticoagulants on the out come of primary repairing arterial injuries due to penetrating trauma of the upper limb 2021-12-22 anticipated 116 Complete https://irct.ir/trial/60178 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization in this study will be done using block randomization method. In this way, patients will be divided into 20 blocks of 6 by Randomization.com online software. Then, in order to hide 20 envelopes with aluminum wrappers (in order to obscure the contents of the envelopes), prepare and create each of random sequences. It is registered on a card and the cards are placed in the envelopes of the order, respectively. In order to maintain a random sequence, the envelopes are numbered in the same way on the outer surface. Finally, the lids of the letter envelopes are glued and placed inside a box, respectively. At the beginning of the registration of participants, based on the order of entry of eligible participants into the study, one of the envelopes of the letter is opened in order and the assigned group of the participant is revealed. 3 Arterial trauma. Intervention 1: Fifty-eight patients will receive a 5,000-unit intravenous heparin treatment during surgery (Chimidaro, Iran) and then receive standard anticoagulant therapy after surgery. Intervention 2: Intervention group: During surgery, 58 patients received 5,000 units of heparin (Chimidaro, Iran) intravenous bolus treatment for once. Then, within 24 hours after surgery, they receive heparin maintenance treatment (Chimidaro, Iran) at a rate of 18 units per kilogram per hour as an intravenous infusion. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information
public Farshad Fereydoon Rajabi
Valiasr Hospital, Valiasr Sq.
Arak Iran (Islamic Republic of) 3814957558 00989632222003 Farshadfereydo@gmil.com Arak University of Medical Sciences scientific Farshad Fereydoon Rajabi
Valiasr Hospital, Valiasr Sq.
Arak Iran (Islamic Republic of) 3814957558 00989632222003 Farshadfereydo@gmil.com Arak University of Medical Sciences Iran (Islamic Republic of) Age less than 30 years Upper extremity vascular injury that requires surgical repair 18 years 30 years Both Existence of multiple injuries in other parts of the body Existence of nerve damage associated with impaired sensory and motor examination Underlying vascular disorders I23.6 Treatment - Drugs Treatment - Drugs Fifty-eight patients will receive a 5,000-unit intravenous heparin treatment during surgery (Chimidaro, Iran) and then receive standard anticoagulant therapy after surgery. Intervention group: During surgery, 58 patients received 5,000 units of heparin (Chimidaro, Iran) intravenous bolus treatment for once. Then, within 24 hours after surgery, they receive heparin maintenance treatment (Chimidaro, Iran) at a rate of 18 units per kilogram per hour as an intravenous infusion. Arterial blood supply. Timepoint: 6 hours after surgery, 24 hours after surgery, at discharge, one week after discharge. Method of measurement: Based on clinical examination criteria for limb color, end pulses, sensation and movement, and capillary filling. Arak University of Medical Sciences Approved 2021-10-25 Ethics committee of Arak University of Medical Sciences Basij sq., Sardasht Town Arak Markazi Iran (Islamic Republic of)