IRCT20080901001165N67 IRCT 2022-02-26 Bagheiat-allah University of Medical Sciences Investigating the effects of zinc sulfate and vitamin C supplementation in sepsis management in septic patients Investigating the effects of zinc sulfate and vitamin C supplementation in sepsis management in septic patients 2022-03-21 anticipated 60 Complete https://irct.ir/trial/60151 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Block randomization method is used for randomization (To do this, go to www.sealedenvelope.com and select the randomization tab and then create a list). Due to the two arms of the study and the sample size, the size of the blocks will be considered as 4, and finally a random list of how the patients are arranged in the two groups will be provided 2 groups , Blinding description: This is a double-blind study in which the prescribing physician and statistical analyzer will unaware of the type of intervention (placebo or drug). The prepared placebo is completely similar in appearance to the main medicine. 3 Sepsis, unspecified organism. Intervention 1: Intervention group: Oral sachet, contains 300mg vitamin C and 10mg Zinc (produced by Bonyan-Salamat-Kasra company), 7 sachets, every 12 hours, PO for 10 days. Intervention 2: Control group: Oral placebo sachet with a quite similarity with intervention sachet (produced by Bonyan-Salamat-Kasra company), 7 sachets, every 12 hours, PO for 10 days. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is The release schedule is not clear yet.