IRCT20150624022896N2 IRCT 2022-01-03 Esfahan University of Medical Sciences Treatment of candida vaginitis Comparison of the effect of 15ppm silver nanoparticles spray (Nivasha) and clotrimazole cream in the treatment of candida vaginitis 2021-12-22 anticipated 100 Complete https://irct.ir/trial/59760 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: First, 100 envelopes are prepared and named equally with codes 1 and 2. The codes are then placed inside the envelopes and sealed in the envelopes. All cards are placed in a box and patients are asked to take a card from the box containing the random allocation cards and deliver it to the questioner. Based on the card number, the women with card number 1, Nivasha spray and the women of card number 2, clotrimazole cream is delivered and how to use it is explained and the drug code is recorded in the questionnaire. 1 candida vaginitis. Intervention 1: Intervention group: Nivasha spray containing 50 cc solution of silver nanoparticles with a concentration of 15 ppm for 10 consecutive days and once a day and 3 puffs each time is prescribed. Intervention 2: Control group: Clotrimazole vaginal cream (1%) one applicator overnight for 7 consecutive nights in lithotomy position will be prescribed. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Most likely, sharing will be done after this study