IRCT20210925052576N1 IRCT 2021-10-07 Islamic Azad University Comparison of Sildenafil and Tadalafil in the treatment of benign prostatic hyperplasia Comparison of Sildenafil and Tadalafil in the treatment of benign prostatic hyperplasia 2021-10-02 anticipated 66 Complete https://irct.ir/trial/58960 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Other, Purpose: Treatment, Other design features: This study is uniquely designed as a single arm study with two consecutive interventions; each patient will be treated with Sildenafil for 6 weeks, then going through a 4 week washout period and lastly, they will be treated with Tadalafil for 6 weeks. The effectiveness of these regiments will be evaluated separately on each patient. Previous studies have shown that prostate size prior to treatment for BPH, profoundly affects the outcome of therapy; therefore, in order to eliminate this confounding factor; every patient will take both drug interventions in consecutive, separate stages and the results will be compared in order to establish the superior treatment choice. 2-3 Benign prostatic hyperplasia (BPH). Intervention 1: Intervention group (first stage) : 50 milligram sildenafil tablet, nightly, for 6 weeks. Intervention 2: Intervention group( second stage) : 5 milligram tadalafil tablet, nightly, for 6 weeks. Yes - There is a plan to make this available What will be shared: all data is shareable after undergoing a anonymity procedure with removal of patients name and surname. When: available from september 2022 To whom: medical researchers Conditions: descriptive analysis is permitted. Where to obtain: email to: mazyar1995@gmail.com How to obtain: evaluation of the resume of the researcher who have asked for the data and emailing the files to them after making sure of their prior experience in medical research. Comments: