IRCT201211065496N2 IRCT 2012-12-05 Craniomaxillofacial Research Center, Tehran University of Medical Sciences Evaluation of effect of using synthetic barrier for plates of reconstructing mandible on frequency of exposure Evaluation of effect of using synthetic membrane for plates of reconstructing mandible on frequency of exposure 2013-01-20 anticipated 36 Complete https://irct.ir/trial/5896 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. N/A Mandibular Reconstruction. adding a synthetic barrier between soft tissue and reconstruction plate.This kind of isolation is routine in reconstructive field of orthopedic surgery with synthetic barrier that have been called ”attachment tube"..

public Dr armita Arvin

Shariati Hospital, department of Oral and maxillofacial Surgery

Tehran Iran (Islamic Republic of) +98 21 8490 2464 armita85@yahoo.com Craniomaxillofacial Reserch Center scientific Ata Garajei

Imam hospital complex-Oprating room of Cancer Institute

Tehran Iran (Islamic Republic of) +98 21 6658 1544 atagarajei@tums.ac.iratagarajei@gmail.com Tehran university of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Patients between 20 and 70 with partial mandibulectomy due to malignant tumor, underwent reconstruction with reconstruction plate and membrane or reconstruction plate and membranre and free vascular flap. These patients will have at least 30 session radiotherapy after surgical procedure. 20 years 70 years Both Z42.0 Follow-up care involving plastic surgery of head and neck Treatment - Surgery adding a synthetic barrier between soft tissue and reconstruction plate.This kind of isolation is routine in reconstructive field of orthopedic surgery with synthetic barrier that have been called ”attachment tube". Plate Exposure. Timepoint: Three monthly. Method of measurement: Observation by one fix observer. Infection. Timepoint: Monthly. Method of measurement: Observation of pus and other sistemic sign and symptom. Recurrence of primary tumor. Timepoint: Monthly. Method of measurement: Observation any sign presentig recurrence. Craniomaxillofacial Research Center, Tehran University of Medical Sciences Approved 2012-11-10 Tehran University of Medical Sciences Keshavarz Blvd Tehran Iran (Islamic Republic of)