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IRCT20200914048713N1 IRCT 2021-11-30 Mashhad University of Medical Sciences Effect of platelet rich fibrin on soft tissue thickness Comparative Evaluation of the effect of platelet rich fibrin and acellular dermal matrix on soft tissue thickness in patients receiving dental implants 2022-01-05 anticipated 20 Complete https://irct.ir/trial/58744 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Block randomization will be done using "randomization.com" website. All data will be placed in opaque sealed envelop and will be opened by nurse before surgery, Blinding description: The person who measures soft tissue thickness at baseline and follow up is totally blind to the type of intervention. Person who analyzes the data is also blind. blinding of the patients and the surgeon is not possible. N/A Thin soft tissue. Intervention 1: Intervention group: 3 layers of platelet rich fibrin will be placed under soft tissue before suturing. Intervention 2: Control group: An acellular dermis membrane with 0.6-1 mm thickness will be placed under patients soft tissue before suturing. No - There is not a plan to make this available Justification or reason for not sharing IPD is Necessary information will be sent to the journal that publishes the article.
public ِAmir Moeein Taghavi
Faculty of dentistry, West door of Ferdowsi University, Vakil Abad street
Mashhad Iran (Islamic Republic of) 9177899191 +98 51 3806 7278 moeentaghavia@mums.ac.ir Mashhad University of Medical Sciences scientific Farid Shiezadeh
Faculty of dentistry, West door of Ferdowsi University, Vakil Abad street
Mashhad Iran (Islamic Republic of) 9177899191 +98 51 3806 7278 fshd1365@gmail.com Mashhad University of Medical Sciences Iran (Islamic Republic of) Patient who need dental implants in posterior mandible Less than 2 mm soft tissue thickness Adequate width and height of the bone healthy soft tissue Lack of previous hard tissue augmentation Lack of previous soft tissue augmentation 18 years 60 years Both Age less than 18 and more than 60 years old Medical contraindication for dental implants Untreated periodontitis Uncontrolled diabetes mellitus Smokers and alcoholic patients Treatment - Other Treatment - Other Intervention group: 3 layers of platelet rich fibrin will be placed under soft tissue before suturing. Control group: An acellular dermis membrane with 0.6-1 mm thickness will be placed under patients soft tissue before suturing. Soft tissue thickness. Timepoint: Baseline, 3 months postoperative. Method of measurement: Endodontic reamer, gauge with 0.1 mm accuracy. Mashhad University of Medical Sciences Approved 2021-08-04 Ethics committee of Mashhad University of Medical Sciences Vakil abad street, vest door of ferdowsi university, faculty of dentistry Mashhad Razavi Khorasan Iran (Islamic Republic of)