IRCT20210912052451N1 IRCT 2021-10-13 Tabriz University of Medical Sciences The effect of normal saline injection in medial nerve epithelium during carpal tunnel syndrome surgery The effect of normal saline injection in medial nerve epithelium during carpal tunnel syndrome surgery 2021-10-23 anticipated 100 Complete https://irct.ir/trial/58703 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Due to the very high prevalence of the disease, patients will be randomly divided into two intervention groups (normal saline injection into endonorium) and the control group (routine surgery without saline injection) using a random number table. Depending on the sample size, which is 100, a 3-digit code will be considered for each sample. Randomization will then be applied using the Rand Company table. N/A carpal tunnel syndrome. Intervention 1: Intervention group: In the intervention group, after the release of the median nerve with minimally invasive carpal tunnel release technique , 0.5 cc of normal saline(commonly used as a sterile 9 g of salt per litre (0.9%) solution) will be injected into the nerve endoneurium with an insulin syringe( 31–29 gauge). Other surgical procedures, according to the usual technique, will be minimally invasive. Intervention 2: Control group: Routine minimally invasive surgery to median nerve release in the carpal tunnel will be performed. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no more information